CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038854
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Tns1 
Protein Synonyms/Alias
  
Gene Name
 Tns1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
221REVAQMLKSKHGGNYacetylation[1]
1160PLSALGLKPHNPADIacetylation[1]
1652EQAIALLKDQEPGAFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1909 AA 
Protein Sequence
MGCTVSLVCC EALEPLPSCG PQPPGTPPGP ARPERSEPGG AASIQRRRLL LQPEDLEAPK 60
THHFKVKAFK KVKPCGVCRQ AITREGCICK VCSFSCHRKC QAKVAAPCVP PSSHELVPIA 120
TESVPKNVVD VGEGDCRGGS TPKNLEEAGS MRVSPSIQPQ PQPQPQPISL SRNLSVSRAM 180
EDSCELDLVY ITERIIAVSF PSTANEENFR SNLREVAQML KSKHGGNYLL FNLSEQRPDI 240
TKLHAKVLEF GWPDLHTPAL EKICSVCKAM DTWLNADPHN VVVLHNKGNR GRIGVVIAAY 300
MHYSNISASA DQALDRFAMK RFYEDKIVPI GQPSQRRYVH YFSGLLSGSI KMNNKPLFLH 360
HVIMHGIPNF ESKGGCRPFL RIYQAMQPVY TSGIYNIPGD SQASICITIE PGLLLKGDIL 420
LKCYHKKFRS PARDVIFRVQ FHTCAIHDLG VVFGKEDLDE AFKDDRFPDY GKVEFVFSYG 480
PEKIQGMEHL ENGPSVSVDY NTSDPLIRWD SYDNFNGHRE DGMEEVVGHT QGPLDGSLYA 540
KVKKKDSLNG SSGPITTARP ALSATPNHVE HTLSVSSDSG NSTASTKTDK TDEPVSGAAI 600
APAALSPQEK KELDRLLSGF GVDREKQGAM YRAQQLRSHP GGGPTVSSPG RHIVPAQVHV 660
NGGALASERE TDILDDELPI QDGQSGGSMG TLSSLDGVTN TSEGGYPETL SPLTNGLDKP 720
YPTEPILNGG GYPYESANRV VPVHSSHSAP IRPSYSAQEG LGGYQREGPH PAWSKQVTSA 780
HRGYDPSGLF RSQSFPDVEP QLPQAPARGG SSREAVQRGL NSWQQQQQQQ QQQQQQQQQQ 840
QQQQPHPPPR QQERSPLQSL ACSKPSPHLS AETPIPALPE FPRAASQQEI EQSIETLNML 900
MLDLEPASAA APLHKSQSVP GAWPGASPLS SQPLLGSSCQ SHPLTQSRSG YIPSGDTLGA 960
PELLSSGRSY SPYDYQLHPA ASNQSFRPKS PASSTFLPSP HSSAGPQEPP ASLPGLIAEP 1020
QLPLKETTSD TSRTPEEEPL NLEGLVAHRV AGVQARERQP AEPPAPLRRR AASDGQYENQ 1080
SPEATSPRSP GVRSPVQCVS PELALTIALN PGGRPKEPHL HSYKEAFEEM EGTSPSSPPP 1140
SVARSPPGLA KTPLSALGLK PHNPADILLH PTGVARRLIQ PEEDEGEEVA KPPEEPRSYV 1200
ESVARTAVAG PRAQDVEPKS FSAPATHAYG HETPLRNGTP GGSFVSPSPL STSSPILSAD 1260
STSVGSFPSA GSSDQGPRTP IQPMLDSSIR SGSLGQPSPA ALSYQSSSPV PVGGSSYSSP 1320
DYSLQPFSSS PESQGQPHFS AASVHMVPGS PQARHRTVGT NTPPSPGFGR RAINPTMAAP 1380
GSPSLSHRQV MGPSGPGFHG NVVSGHPTSA TVAPGSPSLG RHPVGSHQVP GLHSGVVTTP 1440
GSPSLGRHPG AHQGNLVSSL HGNAVISPGS PSLGRHLGGS GSVVPGSPSL DRHVAYGGYS 1500
TPEDRRPTLS RQSSASGYQA PSTPSFPVSP AYYPGLSSPA TSPSPDSAAF RQGSPTPALP 1560
EKRRMSVGDR AGSLPNYATI NGKVSSSPVA NGMASPSGSS TVSFSHTLPD FSKYSMPDNS 1620
PETRAKVKFV QDTSKYWYKP EISREQAIAL LKDQEPGAFI IRDSHSFRGA YGLAMKVSSP 1680
PPTITQQGKK GDMTHELVRH FLIETGPRGV KLKGCPNEPN FGSLSALVYQ HSVIPLALPC 1740
KLVIPSRDPT DESKDSSGPA NSTTDLLKQG AACNVLFINS VDMESLTGPQ AISKATSETL 1800
AADPTPAATI VHFKVSAQGI TLTDNQRKLF FRRHYPLNTV TFCDLDPQER KWMKTEGGAP 1860
AKLFGFVARK QGSTTDNACH LFAELDPNQP ASAIVNFVSK VMLSAGQKR 1909 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR011993; PH_like_dom.
 IPR014019; Phosphatase_tensin-typ.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd.
 IPR013625; PTB.
 IPR006020; PTyr_interaction_dom.
 IPR000980; SH2.
 IPR014020; Tensin_phosphatase_C2-dom. 
Pfam
 PF08416; PTB
 PF10409; PTEN_C2
 PF00017; SH2 
SMART
 SM00109; C1
 SM00462; PTB
 SM00252; SH2 
PROSITE
 PS51182; C2_TENSIN
 PS51181; PPASE_TENSIN
 PS50001; SH2
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS