| Tag | Content |
|---|
| CPLM ID | CPLM-002650 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphate regulon sensor protein PhoR |
Protein Synonyms/Alias | |
Gene Name | phoR |
Gene Synonyms/Alias | nmpB; b0400; JW0390 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 185 | RVMPYTHKQLLMVAR | acetylation | [1] | | 258 | QRMEGLVKQLLTLSK | acetylation | [1] | | 265 | KQLLTLSKIEAAPTH | acetylation | [1] | | 277 | PTHLLNEKVDVPMML | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. |
Sequence Annotation | DOMAIN 96 172 PAS.
DOMAIN 210 425 Histidine kinase.
MOD_RES 213 213 Phosphohistidine; by autocatalysis (By |
Keyword | ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Kinase; Membrane; Nucleotide-binding; Phosphate transport; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Transport; Two-component regulatory system. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 431 AA |
Protein Sequence | MLERLSWKRL VLELLLCCLP AFILGAFFGY LPWFLLASVT GLLIWHFWNL LRLSWWLWVD 60
RSMTPPPGRG SWEPLLYGLH QMQLRNKKRR RELGNLIKRF RSGAESLPDA VVLTTEEGGI 120
FWCNGLAQQI LGLRWPEDNG QNILNLLRYP EFTQYLKTRD FSRPLNLVLN TGRHLEIRVM 180
PYTHKQLLMV ARDVTQMHQL EGARRNFFAN VSHELRTPLT VLQGYLEMMN EQPLEGAVRE 240
KALHTMREQT QRMEGLVKQL LTLSKIEAAP THLLNEKVDV PMMLRVVERE AQTLSQKKQT 300
FTFEIDNGLK VSGNEDQLRS AISNLVYNAV NHTPEGTHIT VRWQRVPHGA EFSVEDNGPG 360
IAPEHIPRLT ERFYRVDKAR SRQTGGSGLG LAIVKHAVNH HESRLNIEST VGKGTRFSFV 420
IPERLIAKNS D 431 |
Gene Ontology | GO:0016021; C:integral to membrane; IDA:EcoCyc. GO:0005886; C:plasma membrane; IDA:EcoCyc. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004721; F:phosphoprotein phosphatase activity; IMP:EcoCyc. GO:0000155; F:phosphorelay sensor kinase activity; IDA:EcoCyc. GO:0016036; P:cellular response to phosphate starvation; IEP:EcoCyc. GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW. GO:0046777; P:protein autophosphorylation; IDA:EcoCyc. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |