Tag | Content |
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CPLM ID | CPLM-005550 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Small nuclear ribonucleoprotein-associated protein B |
Protein Synonyms/Alias | snRNP-B; snRPB; Sm protein B; Sm-B; SmB |
Gene Name | Snrpb |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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32 | RIFIGTFKAFDKHMN | ubiquitination | [1] | 88 | TVEGPPPKDTGIARV | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing (By similarity). Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. |
Sequence Annotation | REPEAT 175 181 REPEAT 191 196 REPEAT 216 221 REPEAT 222 228 REGION 175 228 Repeat-rich region. MOD_RES 108 108 Omega-N-methylated arginine (By MOD_RES 112 112 Dimethylated arginine; alternate (By MOD_RES 112 112 Omega-N-methylated arginine; alternate MOD_RES 147 147 Omega-N-methylarginine (By similarity). |
Keyword | Complete proteome; Methylation; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 231 AA |
Protein Sequence | MTVGKSSKML QHIDYRMRCI LQDGRIFIGT FKAFDKHMNL ILCDCDEFRK IKPKNSKQAE 60 REEKRVLGLV LLRGENLVSM TVEGPPPKDT GIARVPLAGA AGGPGIGRAA GRGIPAGVPM 120 PQAPAGLAGP VRGVGGPSQQ VMTPQGRGTV AAAAAAATAS IAGAPTQYPP GRGGPPPPMG 180 RGAPPPGMMG PPPGMRPPMG PPMGLPPGRG TPMGMPPPGM RPPPPGMRGL L 231 |
Gene Ontology | GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara. GO:0005737; C:cytoplasm; IDA:MGI. GO:0071204; C:histone pre-mRNA 3'end processing complex; IDA:UniProtKB. GO:0005689; C:U12-type spliceosomal complex; IEA:Compara. GO:0005683; C:U7 snRNP; ISS:UniProtKB. GO:0071208; F:histone pre-mRNA DCP binding; IDA:UniProtKB. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. |
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