Tag | Content |
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CPLM ID | CPLM-031776 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | PHD-finger domain-containing protein |
Protein Synonyms/Alias | |
Gene Name | TGME49_024260 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Toxoplasma gondii |
NCBI Taxa ID | 5811 |
Lysine Modification | Position | Peptide | Type | References |
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3651 | VAGEGEGKERSRQSP | acetylation | [1] |
|
Reference | [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii. Jeffers V, Sullivan WJ Jr. Eukaryot Cell. 2012 Jun;11(6):735-42. [ PMID: 22544907] |
Functional Description | |
Sequence Annotation | |
Keyword | Hydrolase; Metal-binding; Methyltransferase; Nucleotidyltransferase; Oxidoreductase; Transferase; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 5306 AA |
Protein Sequence | MAGGSMQRAA RQSRGRSGGR AGGGGGEGAS GSLGDRGCSD TEEERFWIEK DVEFFSAINP 60 RLLALLHHHK QSSEAFLSAV LPYLRSRSRK DAADAAGPSP RSEAAQAFAL RVPVRDFLRQ 120 DWTGGEIGGS VLSGSSAEER RDRRREEIIE RDSDPPKRVA SSPPCRSRSV EENLTERAAF 180 SRDGRSICSK DPQGAREEVS PSCDSLSSPV RRSSSASCLG ISQPVSSEAG SEAGSSSVFA 240 SGATAVAAGF ARTVPTSSGK GAASEGGENS PRSEGGNSVS SRVCSSQGSA PAPVVGCQAH 300 PAPSRLSQVW PHHTGKILLE RPSYSGETGR IIRHMWPATL LADVEPSALC PPPLLRSKKA 360 AADPKKKEDS RAYVRTGVEK KNLEESSRLS CGTEETEARG ESQKRSPDGG RSSQPHSSSV 420 SADLKETNRE TAESQADGSK TDAGLGLCSP WSEETGKTEE EKKDFESQPC GDAGGGRKDG 480 EEDRGGEETP QRSSGAVKEE TNASGEGRLP SGPQSPSKHL DQPGSAAWES SNPRILNGET 540 GSRDGEDSSS SCPEVGTQGP RPTSRRSSVE GRERRSAGLR AASDDKTEKS EDSREKEKDL 600 GAPQPSKDSQ EGQAASVEAT LQNTRTGAPS RAVPTTVLSG VKRELEQDGD TQGPRCGARS 660 PCRASATSPR DEPMSRPAGQ TSSEKWKREE AFCLQVSQNR SIFSLVPGAN DPALLASLHE 720 HQLHAHLKYQ SRDLSVFSHS GDFKRRAASA RGVSRRSGGR RGTRLAAGFD CEETAEGDFS 780 SGSLASSTPS SPAARAAGAR ERERNRRGSD SDFTPSRSEK GDARGDRPAA ARRRDGVSGT 840 VHQKAGSGSP GPSRAGREEV RAGGRTPSGE REPAQRSSSV GREAKAVVEG GEEDPDEAGA 900 DDLFVPTVHK KWNGSMRLPA FPTCRPPDAF VLSMFVPPNV SPADFPEDTN AQGDVSAFLA 960 VVMEAATTTA SDWDAHANTF TPHDGYNLAE KPGDCGPVRA LGKVAAERLG AERNRGTEGL 1020 GLVSREACRG HLLTTAGSCD MQETSRVGSG DSVAQVEAER RAQLERSFAC EGSEARPGHA 1080 RPVATEHPSA SHRRDLSKDG GLVKTPGGGR RRRRSSSTGS GGERTNSGNR RRLKDEKKRS 1140 SGTGAPVSPQ PRSSSGRFMS RQSLTEVSPA APTSSKPRAS VSPSSSLALV SASPRKRPRR 1200 RLPLPTVLSG PLPAWIDCSE RFPGPAPIVH GPRGPSGPFN AGLSFSASHG SCGGQASGLG 1260 MPGPCWGRPV WPETGAPFHI SGDEDPGRAG MNGKRALDKG SETRGGKASD EKREQSQAES 1320 EARLPSSSTT NASPPKHDPP CSSSPPPAER TGPRLEAEGM RSSHALFPPG QSYGGLSPGT 1380 QASGCSPSPG ALFSRASPAG PSSPGSTSSG VHPSQSFASP PSSCPPFAFS GTGPAAPYLA 1440 SGCHPCSFSV RPPACGAAAA FSPASPYAPC RPCAYLPQDA SSGPPPQISG SAYPGAALLS 1500 PPSSAPPGPV CAGPVSEAFS SMRHSFPAAC CPPHPCPPFS SCPPGHPQFC APGNPFSSYP 1560 SEMSPFPELQ RFSSAPPPPC TSFNCPPPYP PPACFPPAPE SSSSSVSSAD FVASFSSSPG 1620 PCRRASSAFS GSTSSEKSEE PPGVSSCQNL GSDATHPPCF SGPTYPVLGG PVDTAFCRPP 1680 PSTAPPGSVP FAAFPPFPCP PLLGLGPVAE FEDRGPVLRS FPFGPASSPA YLTLSLFPRP 1740 SLPAFPGSSA PFEPVSRCSS FLPRGELQTV SSSPPESVAS CLPTPPPEIL VPPFFGAGSS 1800 LKPFPPPCCL YPPEMAENFR YSEKRKMMVP SGVRLELLRA QMTRVDGLHT FYANVETGKR 1860 FFGERSFFEI AKENARRHDA GLQPLSLSPL TSNSATAFFM SVAPETEIPP SGSPNGPHTA 1920 PKKTKATKED SEREEREKRE REEREKRERD EERGRRDLEE KIRIHMYSRH MVPAGSPHLS 1980 GAHRLIPLPW GKRDASRSSP QELEIRARDG DCLHASTGAS AGVGGPQEKK GKTEDAQGEQ 2040 LVSLETAAEP ETQEKKETKA RGVAGVGPSA QSAETASPAP EAACDGQSAE VSPRGDSAAG 2100 RAETGPACGV TGERREVDRE SAQDEGKETE VKTEGPEGAC ETEEFTGCVS VEEGEGCGVK 2160 EITEKAKEGC ASDTANGGTR RELSEKEPGR DKDRVGMHTP FSSEGGEKEN REENGDDRES 2220 ADPFSLKEFN KHRQTSKPVG DVAEPDRVRE ENACPREQAE SEAMDVDGPE ARGELPEGRK 2280 DFEVLSSRNA TETADFDTRQ NEKQKAKGTL VTSTSFGTEV ENLLWRFSAL MDEKRAMCSR 2340 LLMSIEREKR PDWRAWAEVE DRMLRHYIEQ SAKSSLDTRH TYTLTQQSRD ILRLRVSCSS 2400 SGRLPPEWAE RALCTVCGSG EDWDEDPIMF CDGCYQPVHF LCLGHKAVSS YEEFVKASTT 2460 RRQRRVAQAG GDQGLAPATA RERGSGPKRD KKKAAERAKE EKKKGRGGTG DLLASGAFGA 2520 PALGAGSGDA PGASRPAEGD PSGPGASPGD TGHNTRRPVC GAGGFAFRED EEEWLCPVCE 2580 WLRKQLPQLD DELALAAIRL AAGPRSHSEA AECRGSYVGW HFERLEHFDS WVKPQLLALQ 2640 YGDGRRRKGK GRLQVDVGAP QGSRKDTRQG RKVATGLGLP SGDADSVSTL QAHSAYSVQE 2700 LLAWPAVRVV ADAGCLGPNA QSSRSSTSRG SAARGPGTAG ETGGVAGSGG DGSGVFRAEK 2760 DEEDRGLKKP ELDESGGRPS IRGAGPKPCI SSLAQTMLGA RTLPVWATDE ETGKQSCSRE 2820 GSVAGSKGGR LAADGRRLGG GERAGDRCVE PEEDDARRAK GDGDFSRDAW TRGFRSGSET 2880 GMGTSGKGAR EKHPVSLVAP EDATPATDYI RRVPYAFSDS SGDEGPSGKD GDTPFFFCQY 2940 TAGSPTASSP SSAAHRTPSQ EDDSQGGLFS GSAFSPSSAS MRSGAHASGG FSPNSAEPGA 3000 SLTSKHYCSK DPRRRCVVRV FPVPGLSVVL RVPVCALCGY DAFCRGGGPA RKTEKKGVWA 3060 HLRCALSLNA TVMDRVSYEA DESRSRLRCL FCHHQGPAPG HCGHAGCQRT YHVSCATATP 3120 GCMVDWDMGR PVIFCSQHAK NKAPTLILRK FQANREREAV KRREEDLPGE WKIGVGKGRL 3180 GIALQSLLFP SYDGLCNVFS DLLEVPTLRL PTLSPAEKKV TSQGLEALSF PGADPALGAP 3240 RDEAEALERR HRAQSREEKA TGVDEQRRGN AQTEDAAHRE KEEKGRNLEG SSVARGEAES 3300 GGGPDEEEER FTRRLTWRRR RVADSDAEDL EGKETKKKCP EEKAAGRTAE GADASVETSR 3360 DCGMEGESAS TAHAKQEVLD AGELRRETEG DSSPPSHSPK NVMVGEGVDN SRFPRASLEE 3420 QEWKKEKAEE KERRNWEKPE VIQSGLPSGE REEVCQSVGA AASREQGLSG SHAAHKEPQK 3480 EAEVSCLSST RDMTRVREAR EEPTFENRGK NDQTKPAEAE DRGNVRVDEF RLSRSPENES 3540 RLLSSLQKDR DEDKIEESEN RLAGARGTGE LRSDPTSASS SSAVNTVAGA DPGREVENVV 3600 AENCSSPSSF PGGQDDTLSF VLQERERSEA AAVLGKSESA TDAVAGEGEG KERSRQSPNG 3660 CGAGEETRDD ESRLDRQSGS TTDAPPLFLP SGSSDLLSLP PSLRLGETAG RCLPNGPAPP 3720 GEGVSEPVSS RVGSVLEGGT GARRGECVSH SQAGTSREQG GVSRGESDTA TPFSSGGETG 3780 ASHADEKPQR GPHSSLNFFA ALDLEGGRTQ NAAPGHKGTL ASPTGVAAPF GDPLENSPQN 3840 LFEANTSKSP FSPDGWGEAA FFSSASSFRS FSFTSGNPPG SSSEPAAPPR KRRGRPPLSR 3900 RSQGATHKDA VHRQDRDRVS SYLKMAAGGA LSRGGRFSLG GSCDRDKRRS LHLGGGRGSG 3960 MNLPERGPGG RFLPRGHREK NAQQTPVSDS VSTSSYQKQR PVSLSDPSQE GSADRRDGGD 4020 SGGENESQEN RELQAREEAL HQQRMRYMQM LFHLQALTRE RHRRLLGNDF ALTGLLLGSP 4080 DPAGAFDPGA LHAAGLPPTP LHGSSPATFF ARRVARLLDS PAPLAIRRSS TNGSAGTAGE 4140 EKVRGAPGGV GQADTATVET GVEEGPSGRA GAERGTGGAQ EENDEKEEKK ESVSGVSSCA 4200 ADANPDAGNR AKEARTKEAS ACVALASFSS PVDYLRLTTI KDWGLPQHTG DEKLFKCAFE 4260 ETKAANVLGI ETYDRFLARQ GVQSVARLLD AVVDLLLFFI LRGVCCAGPS PALLAALSEG 4320 KSLPQSRVPG GFVFPLALQL AGGSPAGGQK AKRAEGPGGS ERLCEAEEET EDSQREGKTP 4380 SAPLASSEEE PLYALIDTVR QLGQVAELDF KTGTDAIQKE EGAKKQLAVK REEPSVGTDD 4440 DEDEDELDEM KKRRSRTKQE KNAIATRRRQ TSAERDREQE MQERLREEDE TDWTCLRCAA 4500 VLNVGTPFPS TRCILCSRID GLLVRRIPED TPSLSNKKSG AFHVSCARQL GCRMETQRRS 4560 LDQQIHRAYC LEHTTQMNRK LLQQRLASHK PFAFPQRKDT LDLNRFFDPL QLLIADPIRS 4620 ITSLFLVGIH LERLAPPSLT SFAAFMRPSS LRLSSAEGGK QGEKEKRCRE AFGARGALHT 4680 SGRVDEQRAR YLKTGTHRPE ETGSVSWNAF DENDAFFEAV RERKKQRHGR REEGVGDRTR 4740 TGASAWSEGE REGRRERGLE SGDDYAASSA CDPLLTPGPP SPLHLEEQRE LYCTGVAICD 4800 ALYTQSRAFE EEALNLPSPS RSEVDAARAL YCVSEPASPD LRDRQRWTSA FEVTDGLMDD 4860 ENEKTTAGRT SSGSTSLERG RGVAWESGSK RRRVSLSSGS GGPPYFSGDA LSSVKDRVPP 4920 SCLTRSGLRS SLVSAAHASH FFDAGEDRGN QLVTPLESQK RVIDPARLTW SPQESVRRPS 4980 FVARAGLDGA VCLHDGGEAL PAPALTLSAE DSEAPTEEKR QSRDTGKALK FTQDAGNESS 5040 EKESRFSPDQ SLPHSDAESS GANAWGVSPS PALPSDGDSS GPRATASQTV SAVSCDSESI 5100 VLPPYLLRGT AVDLPSLTED VSPAASASAV LASESWYRGI SAAASMAVAH AVQAVSSRGD 5160 LDADEAEGAA REREEKQNGE SFDVLANLHI GSPGQVQGEK QPIFCPICKG MYNELPDGGP 5220 GDGFAWVGCD CCERWYHWTC SGFNEENPPP DDCDWICWFC TVKIRKKEEQ ERERQAHGLQ 5280 VKDKHRSGIK HSRSRPPPRK RDRSKR 5306 |
Gene Ontology | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. GO:0004720; F:protein-lysine 6-oxidase activity; IEA:EC. GO:0003968; F:RNA-directed RNA polymerase activity; IEA:EC. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0034968; P:histone lysine methylation; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |