CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016957
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytokine receptor-like factor 3 
Protein Synonyms/Alias
 Cytokine receptor-like molecule 9; CREME-9; Cytokine receptor-related protein 4; Type I cytokine receptor-like factor p48 
Gene Name
 CRLF3 
Gene Synonyms/Alias
 CREME9; CRLM9; CYTOR4; P48 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
56SQTRDVLKQHFNDLKubiquitination[1]
68DLKGTLGKLLDERLVubiquitination[1]
191QIEELIEKPGGIIVRubiquitination[1]
339SIGVCAEKQDGYDSLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May play a role in the negative regulation of cell cycle progression. 
Sequence Annotation
 DOMAIN 178 268 Fibronectin type-III.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 442 AA 
Protein Sequence
MRGAMELEPE LLLQEARENV EAAQSYRREL GHRLEGLREA RRQIKESASQ TRDVLKQHFN 60
DLKGTLGKLL DERLVTLLQE VDTIEQETIK PLDDCQKLIE HGVNTAEDLV REGEIAMLGG 120
VGEENEKLWS FTKKASHIQL DSLPEVPLLV DVPCLSAQLD DSILNIVKDH IFKHGTVASR 180
PPVQIEELIE KPGGIIVRWC KVDDDFTAQD YRLQFRKCTS NHFEDVYVGS ETEFIVLHID 240
PNVDYQFRVC ARGDGRQEWS PWSVPQIGHS TLVPHEWTAG FEGYSLSSRR NIALRNDSES 300
SGVLYSRAPT YFCGQTLTFR VETVGQPDRR DSIGVCAEKQ DGYDSLQRDQ AVCISTNGAV 360
FVNGKEMTNQ LPAVTSGSTV TFDIEAVTLG TTSNNEGGHF KLRVTISSNN REVVFDWLLD 420
QSCGSLYFGC SFFYPGWKVL VF 442 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
 GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
 GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold. 
Pfam
  
SMART
 SM00060; FN3 
PROSITE
 PS50853; FN3 
PRINTS