CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013063
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Monocarboxylate transporter 10 
Protein Synonyms/Alias
 MCT 10; Aromatic amino acid transporter 1; Solute carrier family 16 member 10; T-type amino acid transporter 1 
Gene Name
 Slc16a10 
Gene Synonyms/Alias
 Mct10; Tat1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
488AGGEKMEKMLENQSSubiquitination[1]
505SGSSGIFKKDSASIIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. 
Sequence Annotation
 MOD_RES 266 266 Phosphoserine.
 MOD_RES 495 495 Phosphoserine.
 MOD_RES 501 501 Phosphoserine.  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 512 AA 
Protein Sequence
MVPSQEEPAA ERETNEAQPP GPAPSDDAPL PGPGPSDVSD VAAEKVEVEL TRSAGSEPPV 60
PPEGGWGWLV MLAAMWCNGS VFGIQNAYGV LFVSMLDTFK AKDDDNMAFK TAWVGSLSMG 120
MIFFCCPIVS VFTDMFGCRR TAVVGAAVGF IGLMSSSFVS SIEPLYLTYG IIFACGCSFA 180
YQPSLVILGH YFKKRLGLVN GIVTAGSSVF TILLPLLLGN LISSVKLFNT LRILCIFMFV 240
LFLAGFTYRP LVPSTKEKES GGSRSSFFSR RKLSPPKKVF NFALFKETTY AVWAAGIPLA 300
LFGYFVPYVH LMNHVKERFQ DVNNKEVLFM CIGITSGVGR LLFGRIADYL PGVKKVYLQV 360
LSFFFIGLMS MMIPLCSAFG ALIAVCLAMG LFDGCFISIM APIAFELVGP QDASQAIGFL 420
LGFMSIPMTV GPPIAGLLHD KLGTYDVAFY LAGIPPFVGG VVLCLIPWIH SKKQRKISKN 480
AGGEKMEKML ENQSSLLSGS SGIFKKDSAS II 512 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS