UniProt Accession

 E9PIA7_HUMAN; E9PIA7 

Genbank Protein ID

 AP006284 

Genbank Nucleotide ID

  

Protein Name

 Interferon regulatory factor 7 

Protein Synonyms/Alias

  

Gene Name

 IRF7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
61	EADARIFKAWAVARG	ubiquitination	[1]
92	TAERAGWKTNFRCAL	ubiquitination	[1]
120	GDPADPHKVYALSRE	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 

Interpro

 IPR019817; Interferon_reg_fac_CS.
 IPR001346; Interferon_reg_fact_DNA-bd_dom.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00605; IRF 

SMART

 SM00348; IRF 

PROSITE

 PS00601; IRF_1
 PS51507; IRF_2 

PRINTS

 PR00267; INTFRNREGFCT.