CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Interferon-activable protein 204 
Protein Synonyms/Alias
  
Gene Name
 Ifi204 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
210IPSAKNQKSQPQNQNubiquitination[1]
556NKKTERNKFIYYGIGacetylation[2, 3, 4]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 619 AA 
Protein Sequence
MVNEYKRIVL LRGLECINKH YFSLFKSLLA RDLNLERDNQ EQYTTIQIAN MMEEKFPADS 60
GLGKLIAFCE EVPALRKRAE ILKKERSEVT GETSLEKNGQ EAGPATPTST TSHMLASERG 120
ETSATQEETS TAQAGTSTAQ ARTSTAQAGT STAQKRKIMR EEETGVKKSK AAKEPDQPPC 180
CEEPTARCQS PILHSSSSAS SNIPSAKNQK SQPQNQNIPR GAVLHSEPLT VMVLTATDPF 240
EYESPEHEVK NMLHATVATV SQYFHVKVFN INLKEKFTKK NFIIISNYFE SKGILEINET 300
SSVLEAAPDQ MIEVPNSIIR NANASPKICD IQKGTSGAVF YGVFTLHKKT VNRKNTIYEI 360
KDGSGSIEVV GSGKWHNINC KEGDKLHLFC FHLKTIDRQP KLVCGEHSFI KISKRGNVPK 420
EPAKEEDHHH GPKQVMVLKV TEPFTYDLKE DKRMFHATVA TETEFFRVKV FDTALKSKFI 480
PRNIIAISDY FGCNGFLEIY RASCVSDVNV NPTMVISNTL RQRANATPKI SYLFSQARGT 540
FVSGEYLVNK KTERNKFIYY GIGDDTGKME VVVYGRLTNV RCEPGSKLRL VCFELTSTED 600
GWQLRSVRHS YMQVINARK 619 
Gene Ontology
  
Interpro
 IPR004020; DAPIN.
 IPR004021; HIN200/IF120x.
 IPR012340; NA-bd_OB-fold. 
Pfam
 PF02760; HIN
 PF02758; PYRIN 
SMART
  
PROSITE
 PS50824; DAPIN
 PS50834; HIN_200 
PRINTS