CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017152
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein 17 
Protein Synonyms/Alias
  
Gene Name
 WDR17 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
802AQELTTVKMSKFGGGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 REPEAT 81 121 WD 1.
 REPEAT 123 164 WD 2.
 REPEAT 171 211 WD 3.
 REPEAT 221 261 WD 4.
 REPEAT 266 307 WD 5.
 REPEAT 391 431 WD 6.
 REPEAT 434 474 WD 7.
 REPEAT 478 518 WD 8.
 REPEAT 519 559 WD 9.
 REPEAT 564 604 WD 10.
 REPEAT 607 647 WD 11.
 REPEAT 650 690 WD 12.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1322 AA 
Protein Sequence
MAWMTYISNW FEQDDWYEGL QRANMSQVRQ VGLLAAGCQP WNKDVCAASG DRFAYCATLA 60
IYIYQLDHRY NEFKLHAIMS EHKKTITAIS WCPHNPDLFA SGSTDNLVII WNVAEQKVIA 120
KLDSTKGIPA SLSWCWNAED VVAFVSHRGP LFIWTISGPD SGVIVHKDAH SFLSDICMFR 180
WHTHQKGKVV FGHIDGSLSI FHPGNKNQKH VLRPESLEGT DEEDPVTALE WDPLSTDYLL 240
VVNLHYGIRL VDSESLSCIT TFNLPSAAAS VQCLAWVPSA PGMFITGDSQ VGVLRIWNVS 300
RTTPIDNLKL KKTGFHCLHV LNSPPRKKFS VQSPTKNHYT SSTSEAVPPP TLTQNQAFSL 360
PPGHAVCCFL DGGVGLYDMG AKKWDFLRDL GHVETIFDCK FKPDDPNLLA TASFDGTIKV 420
WDINTLTAVY TSPGNEGVIY SLSWAPGGLN CIAGGTSRNG AFIWNVQKGK IIQRFNEHGT 480
NGIFCIAWSH KDSKRIATCS SDGFCIIRTI DGKVLHKYKH PAAVFGCDWS QNNKDMIATG 540
CEDTNVRVYY VATSSDQPLK VFSGHTAKVF HVKWSPLREG ILCSGSDDGT VRIWDYTQDA 600
CINILNGHTA PVRGLMWNTE IPYLLISGSW DYTIKVWDTR EGTCVDTVYD HGADVYGLTC 660
HPSRPFTMAS CSRDSTVRLW SLTALVTPVQ INILADRSWE EIIGNTDYAI EPGTPPLLCG 720
KVSRDIRQEI EKLTANSQVK KLRWFSECLS PPGGSDNLWN LVAVIKGQDD SLLPQNYCKG 780
IMHLKHLIKF RTSEAQELTT VKMSKFGGGI GVPAKEERLK EAAEIHLRLG QIQRYCELMV 840
ELGEWDKALS IAPGVSVKYW KKLMQRRADQ LIQEDKDDVI PYCIAIGDVK KLVHFFMSRG 900
QLKEALLVAQ AACEGNMQPL HVSVPKGASY SDDIYKEDFN ELLHKVSKEL AEWYFQDGRA 960
VLAACCHLAI DNIELAMAYL IRGNELELAV CVGTVLGESA APATHYALEL LARKCMMISV 1020
CFPCVGYSVP FCYVNRNLAA DLLLMIPDNE LHLIKLCAFY PGCTEEINDL HDKCKLPTVE 1080
ECMQLAETAR ADDNIFETVK YYLLSQEPEK ALPIGISFVK EYISSSDWTL DTIYPVLDLL 1140
SYIRTEKLLL HTCTEARNEL LILCGYIGAL LAIRRQYQSI VPALYEYTSQ LLKRREVSVP 1200
LKIEYLSEEL DAWRACTQST NRSLEDSPYT PPSDSQRMIY ATLLKRLKEE SLKGIIGPDY 1260
VTGSNLPSHS DIHISCLTGL KIQGPVFFLE DGKSAISLND ALMWAKVNPF SPLGTGIRLN 1320
PF 1322 
Gene Ontology
  
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.