UniProt Accession

 E9Q4N8_MOUSE; E9Q4N8 

Genbank Protein ID

 AC127690 

Genbank Nucleotide ID

  

Protein Name

 Vascular endothelial growth factor A 

Protein Synonyms/Alias

  

Gene Name

 Vegfa 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
146	EKKSVRGKGKGQKRK	acetylation	[1]
148	KSVRGKGKGQKRKRK	acetylation	[1]
151	RGKGKGQKRKRKKSR	acetylation	[1]

Reference

 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Growth factor; Mitogen; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005615; C:extracellular space; IDA:MGI.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0046982; F:protein heterodimerization activity; ISO:MGI.
 GO:0048844; P:artery morphogenesis; IMP:MGI.
 GO:0048593; P:camera-type eye morphogenesis; IMP:MGI.
 GO:0048739; P:cardiac muscle fiber development; IMP:MGI.
 GO:0048469; P:cell maturation; IMP:MGI.
 GO:0016477; P:cell migration; IDA:MGI.
 GO:0008283; P:cell proliferation; IMP:MGI.
 GO:0071456; P:cellular response to hypoxia; ISO:MGI.
 GO:0071542; P:dopaminergic neuron differentiation; IGI:MGI.
 GO:0030855; P:epithelial cell differentiation; IMP:MGI.
 GO:0042462; P:eye photoreceptor cell development; IMP:MGI.
 GO:0040007; P:growth; IMP:MGI.
 GO:0003007; P:heart morphogenesis; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0001822; P:kidney development; IMP:MGI.
 GO:0007595; P:lactation; IMP:MGI.
 GO:0030324; P:lung development; IDA:MGI.
 GO:0060749; P:mammary gland alveolus development; IMP:MGI.
 GO:0007498; P:mesoderm development; IMP:MGI.
 GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.
 GO:0001541; P:ovarian follicle development; IMP:MGI.
 GO:0001569; P:patterning of blood vessels; IMP:MGI.
 GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.
 GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
 GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:MGI.
 GO:1901492; P:positive regulation of lymphangiogenesis; IDA:MGI.
 GO:0002053; P:positive regulation of mesenchymal cell proliferation; IDA:MGI.
 GO:0002052; P:positive regulation of neuroblast proliferation; IGI:MGI.
 GO:0043117; P:positive regulation of vascular permeability; IDA:MGI.
 GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.
 GO:0060319; P:primitive erythrocyte differentiation; IMP:MGI.
 GO:0043129; P:surfactant homeostasis; IMP:MGI.
 GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IDA:MGI. 

Interpro

 IPR000072; PD_growth_factor.
 IPR023581; PD_growth_factor_CS. 

Pfam

 PF00341; PDGF 

SMART

 SM00141; PDGF 

PROSITE

 PS00249; PDGF_1
 PS50278; PDGF_2 

PRINTS