CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034751
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Usp13 
Gene Synonyms/Alias
 Usp13_predicted; rCG_41305 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
326QESGTKLKPMYGPGYubiquitination[1]
638IVIPDDSKDRLMNQLubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 858 AA 
Protein Sequence
MQRRGALFSV PGGGGKMAAG DLGELLVPHM PTIRVPRSGD RVYKNECAFS YDSPNSEGGL 60
YVCMNTFLAF GREHVERHFR KTGQSVYMHL KRHMREKVRG ASGGALPKRR NSKLFLDLDM 120
DDDLNSDDYE YEDEAKLVIF PDHYEIALPN IEELPALVTI ACDAVLSSKS PYRKQDPDTW 180
ENELPVSKYA NNLVQLDNGV RIPPSGWKCA RCDLRENLWL NLTDGSVLCG KWFFDSSGGN 240
GHALEHYRDM GYPLAVKLGT ITPDGADVYS FQEEGPVSDP HLAKHLAHFG IDMLHTQGTE 300
NGFRDNDIKL RVSEWEVIQE SGTKLKPMYG PGYTGLKNLG NSCYLSSVMQ AIFSIPEFQR 360
AYVGNLPRIF DYSPLDPTQD FNTQMTKLGH GLLSGQYSKP PVKSELIEQV MKEEHKPQQN 420
GISPRMFKAF VSKSHPEFSS NRQQDAQEFF LHLVNLVERN RIGSENPSDV FRFLVEERIQ 480
CCQTRKVRYT ERVDYLMQLP VAMEAATNKD ELIAYELMRR EAETNRRPLP ELVRAKIPFS 540
ACLQAFAEPD NVDDFWSSAL QAKSAGVKTS RFASFPEYLV VQIKKFTFGL DWVPRKFDVS 600
IDMPDLLDIS HLRARGLQPG EEELPDISPP IVIPDDSKDR LMNQLIDPSD IDESSVMQLA 660
EMGFPLEACR KAVYFTGNTG AEVAFNWIIV HMEEPDFAEP LAIPGYGGAG ASAFGATGLD 720
NQPPEEIVAI ITAMGFQRSQ AVQALQATNH NLERALDWIF SHPEFEEDSD FVIEMENNAN 780
ANIMSEAKPE GPRVKDGSGM YELFAFISHM GTSTMSGHYV CHIKKEGRWV IYNDHKVCAS 840
ERPPKDLGYM YFYRRIPS 858 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19.
 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N.
 IPR015940; UBA/transl_elong_EF1B_N_euk.
 IPR016652; Ubiquitinyl_hydrolase.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001607; Znf_UBP. 
Pfam
 PF00627; UBA
 PF00443; UCH
 PF02148; zf-UBP 
SMART
 SM00165; UBA
 SM00290; ZnF_UBP 
PROSITE
 PS50030; UBA
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3
 PS50271; ZF_UBP 
PRINTS