CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038755
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cullin-9 
Protein Synonyms/Alias
  
Gene Name
 Cul9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
574LNSRIYTKYGLLPKEubiquitination[1]
1454QPLSKNSKGQDGSPTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2520 AA 
Protein Sequence
MVGERRAGNL LVPLGPRLQA YPEELLRQRP GHDGHPEYLI RWSVLKCSEE GKVSSEEEKT 60
EHLLMWLSAP EVYANCPMLL RERPIPKGPQ HEPAGEVGSF PRDPGGLDEL AMTEMEADVR 120
ALVRRAARQL AEGGTSSLTA AVLHTVHVLS AYASIGPLTG VFRETGALDL LMHMLCNPEP 180
QIRRSAGKML QALAAHDAGS RAHVLLSLSQ HDGIEQHMDF DSRYTLLELF AETTSTEEHC 240
MALEGIHLPQ IPGKLLFSLV KRYLCVTSLL DQLNNSPESG AGDQSSPCLT KEKSRAQQEL 300
EFSMAVGNLI SELVRSMGWA RNLSEQGALP PRPSRSIFQP CLSGPPPLLL PTIVTTPRKQ 360
GRAFRGRSEF SSRSGYGEYV QQTVQPGMRV RILDDYEEIS AGDEGEFQQS NNGVPPVQVF 420
WQSTGRTYWV HWHMLEILGP EEATGDSASA AVEKGAGAAV LGTVCPSWDW KPTHGLYSLP 480
YLQPEPQKNE EESGYLTQAE WWELLFFIKK LDVGEQQPIF QNLHEKLDEE ALGEKALGEL 540
SVPIEMAEGV LQVLSNRFEG SNLCDLLNSR IYTKYGLLPK ELGSLPSSRR HSCSPEPEEG 600
SRSAANFSEK EEACRANAVP PEAEMELASA KTEPPKAQSD SQLFNQLLVT EGMTLPPETQ 660
EAATEMARAL RGPGPRSSLD QHVAAVLATV QISSLDTNLQ LSGLCALSQA VEEVTERDHP 720
LVRPDRPLRE KLVKTLVDLL TNQVGEKMVV VMALRLLYLL MTKHEWRPLF AREGGIYAVL 780
ICMQEYKTSV LVQQAGLAAL KMLAIANSSD VPTFIPSRDS IQPLFDTQMT REIFASIDSA 840
TRPGSESLLL SVPAAVVLML NTEGCSSAVR NGLLLLNLLL CNHHTLGDQI ITQELRDTLF 900
RHSGIAPGTE PMPTTRTILT MLLSRYSEPR GSPERAVLET PSTQGQDGSP ESLIRSLVGD 960
LSAELFLDLE RVLCHEGSPP AAVRPLLRRL QQETQPFLLL LRTLDAPGPN RTLLLTILRV 1020
MTRLLDHPET MVLPWHEVLE PCLNCLNGPS SDSEVVQEVT CFLHRLALMQ KDYAVVLCCL 1080
GGKEALSKVL DKHSTQLLLA SELRHLVAEC EKYSQLCSNL TSSILAGCIQ MVLGQIEDHR 1140
RTYKPITIPF FDVFLRHLCQ GSSVEVKEDR CWEKVEVSSN PHRASKLTDR NPKTYWESNG 1200
STGSHSITLH MHRGVLIRQL TLLVASEDSS YMPARVVVFG GDNVGCISTE LNTVNVMPSA 1260
SRVTLLENLT RFWPIIQIRI KRCQQGGIDT RVRGVEVLGP KPTFWPLFRE QLCRRTCLFY 1320
TIRAQAWSRD IAEDRQRLLQ LYPRLNRVLR HEQNFADRFL PDDEAAQALG KTCWEALVSP 1380
LVQNITSPDA GGVSSLGWLL DQYLEHREST RSRQGPAASF ASQVRRLCHL LVHVEAPPGP 1440
SPEPSSQPLS KNSKGQDGSP TPAPTPVCPS TSLRNLTQCW LSVVQGQVSR FLAAAWRASD 1500
FVPRYCSLYQ RLQSAGSELF GPRAAFTLAL RSGFSGALLQ QSFLTAAHIS EQFARHIDQQ 1560
IHGGLLGGAA GVGMLGRLQR HLEPIMVLSG LELATTFEHF YQHYMADRLL SLGSSWLEGA 1620
VLEQIGPCFP NRLPQLMLQS LHTSEELQHR FHLFQLQQLD RQLLEQGDQE EWRPEKVEED 1680
DEGQETGREL FTDPGPAISV LVLSPRCWPV SPLCYLHHPR KHLQAELCDA LERFSSFYSH 1740
SQNCPVLDIG PHRRLQWTWL GRAELQFGDQ TLHVSTVQMW LLLNFNQSEE VSVETLLRNS 1800
DLSPELLHQA LLPLTSDNGP LTLEETQDYP QGGVLRLREP RSQTHEEVLW LIPPQTYLSV 1860
EKDEGRTLEQ KRNLLSCLLV RILKAHREKG LHIDQLVCLV LEAWQKGPDP PGRLGNAAAV 1920
GVACSSTDVL SCILHLLGQG YVERRDDRPQ VLMYATPEPM GPCRGQADVP FCGNKNTETS 1980
RPSPEAVVAL ASLQLPAGRT MSPQEVEGLM EQTVRQVQET LNLEPDVAQH LLAHSHWGTE 2040
QLLQSYSDDP EPLLLAAGLR VPQAQVVPTR PDQCPVCVTP LGPHDDSPSL CCLHCCCKSC 2100
WNEYLTTRIE QNFVLNCTCP IADCPAQPTG AFIRNIVSSP EVISKYEKAL LRGYVESCSN 2160
LTWCTNPQGC DRILCRQGLG SGTTCSKCGW ASCFSCSFPE AHYPASCGHM SQWVDDGGYY 2220
DGMSVEAQSK HLAKLISKRC PSCQAPIEKN EGCLHMTCAR CNHGFCWRCL KSWKPSHKDY 2280
YNCSAMVSKA ARQEKRFQDY NERCTFHHQA REFAVNLRNQ ASAIQEVPPP KSFTFLQDAC 2340
RALEQARKVL AYACVYSFYS QDTEYMDVVE QQTENLELHT NALQILLEET LLRCRDLASS 2400
LRFLRADCLS TGTELLRRIQ ERLLAILQHS TQDFRVGLQS PSVETREVKG SNVPSDQPQG 2460
SSGLEEEEEE EEEEEDVPEW QHEFDEELDN DSFSYDEESE NLDRETFFFG DEDEDDESYD 2520 
Gene Ontology
 GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR004939; APC_su10/DOC_dom.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR021097; CPH_domain.
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR008979; Galactose-bd-like.
 IPR014722; Rib_L2_dom2.
 IPR011991; WHTH_DNA-bd_dom.
 IPR002867; Znf_C6HC.
 IPR001841; Znf_RING.
 IPR017907; Znf_RING_CS. 
Pfam
 PF03256; APC10
 PF11515; Cul7
 PF00888; Cullin
 PF01485; IBR 
SMART
 SM00884; Cullin_Nedd8
 SM00647; IBR 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2
 PS51284; DOC
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS