CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongation factor Tu 
Protein Synonyms/Alias
  
Gene Name
 TGGT1_007730, TGVEG_072470 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
552VTKPMPEK*******acetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Elongation factor; GTP-binding; Nucleotide-binding; Nucleotidyltransferase; Protein biosynthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 552 AA 
Protein Sequence
MATNLILRFR VGVSRPHTAA VGAAVPFCRA SVAVPFCSSI RDFSASSSCA LSSRLVSPSL 60
SPRLNAPVAC SQFSGLARTV ERTGRRPAAS ESRPSRRFAS LFSSDSSSSP ALFSASSTPA 120
LHSPVSPAFS TALSTSRVSA LADCSRLLEA KRGFAVGVFQ RTKPHLNIGT IGHVDHGKTT 180
LTAAITKVLA DMGQADFKSY AEIDKSPEEQ KRGITINATH VEYETSKRHY GHVDCPGHAD 240
YVKNMITGAA QMDGAILVVS AYDGPMPQTR EHILLSKQVG VPRLVVYLNK MDMVEDQELV 300
ELVEMEVREL LSFYDFPGDD TPFVKGSALK ALNGDTGEYG IKTIQDLMQA CDDFIPEPER 360
KADLPLIIPV ESVLSIPGKG TVATGRVEQG TAKPNEAIEI VGGRDKPLKA QIAALEMFRK 420
TLDDAQAGDQ VGCLLKGIKR DEVKRGMVLG APGYLKTFKK FEADLYVLKE EEGGRKKPFF 480
SHYRPQAFIR TGDMACTITL PETTEMAMPG DRVSCTVELL HPTALHEGLR FALREGGRTV 540
ASGIVTKPMP EK 552 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
 GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR009001; Transl_elong_EF1A/Init_IF2_C.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR004541; Transl_elong_EFTu/EF1A_bac/org.
 IPR004160; Transl_elong_EFTu/EF1A_C.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2
 PF03143; GTP_EFTU_D3 
SMART
  
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.