CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010702
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxisomal targeting signal 2 receptor 
Protein Synonyms/Alias
 PTS2 receptor; Peroxin-7 
Gene Name
 Pex7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
181TLRIWDVKTTGVRIVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. 
Sequence Annotation
 REPEAT 60 91 WD 1.
 REPEAT 104 136 WD 2.
 REPEAT 148 179 WD 3.
 REPEAT 191 222 WD 4.
 REPEAT 235 266 WD 5.
 REPEAT 279 310 WD 6.  
Keyword
 Complete proteome; Cytoplasm; Peroxisome; Protein transport; Reference proteome; Repeat; Transport; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MSAARTLRVP GRHGYAAEFS PYLPGRLACA AAQHYGIAGC GTLLVLDQNE SGLQIFRSFD 60
WNDGLFDVTW SENNEHVLVT CSGDGSLQLW DTAKATGPLQ VYKEHTQEVY SVDWSQTRGE 120
QLVVSGSWDQ TVKVWDPTVG NSLCTFRGHE SVIYSTIWSP HIPGCFASAS GDQTLRIWDV 180
KTTGVRIVIP AHQTEILSCD WCKYNENLVV TGAVDCSLRG WDLRNVRQPV FELLGHTYAI 240
RRVKFSPFHA SVLASCSYDF TVRFWNFSKP DPLLETVEHH TEFTCGLDLS LQSPTQVADC 300
SWDETIKIYD PVCLTVPG 318 
Gene Ontology
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0005782; C:peroxisomal matrix; IEA:Compara.
 GO:0005053; F:peroxisome matrix targeting signal-2 binding; IEA:Compara.
 GO:0001958; P:endochondral ossification; IMP:MGI.
 GO:0008611; P:ether lipid biosynthetic process; IEA:Compara.
 GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.
 GO:0001764; P:neuron migration; IMP:MGI.
 GO:0016558; P:protein import into peroxisome matrix; IMP:MGI. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.