UniProt Accession

 C9JAX1_HUMAN; C9JAX1 

Genbank Protein ID

 AL162730 

Genbank Nucleotide ID

  

Protein Name

 Frataxin, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 FXN 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
122	LTKALKTKLDLSSLA	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 135 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0004322; F:ferroxidase activity; IEA:InterPro.
 GO:0007628; P:adult walking behavior; IEA:Compara.
 GO:0009060; P:aerobic respiration; IEA:Compara.
 GO:0006879; P:cellular iron ion homeostasis; IEA:Compara.
 GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Compara.
 GO:0016226; P:iron-sulfur cluster assembly; IEA:Compara.
 GO:0007005; P:mitochondrion organization; IEA:Compara.
 GO:0040015; P:negative regulation of multicellular organism growth; IEA:Compara.
 GO:0046621; P:negative regulation of organ growth; IEA:Compara.
 GO:0006119; P:oxidative phosphorylation; IEA:Compara.
 GO:0045773; P:positive regulation of axon extension; IEA:Compara.
 GO:0019230; P:proprioception; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0014070; P:response to organic cyclic compound; IEA:Compara. 

Interpro

 IPR017789; Frataxin.
 IPR002908; Frataxin/CyaY.
 IPR020895; Frataxin_CS. 

Pfam

 PF01491; Frataxin_Cyay 

SMART

  

PROSITE

 PS01344; FRATAXIN_1
 PS50810; FRATAXIN_2 

PRINTS

 PR00904; FRATAXIN.