CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009149
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 182 kDa tankyrase-1-binding protein 
Protein Synonyms/Alias
  
Gene Name
 Tnks1bp1 
Gene Synonyms/Alias
 Kiaa1741; Tab182 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
167TVEEILAKMEQPRKEacetylation[1]
1263AEAGEFLKSRERGVGubiquitination[2]
1648GLSPSALKAKLRSRNubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 REGION 209 1563 Acidic.
 REGION 1440 1532 Tankyrase-binding (By similarity).
 MOTIF 1620 1626 Nuclear localization signal (Potential).
 MOTIF 1714 1719 Nuclear localization signal (Potential).
 MOD_RES 178 178 Phosphoserine (By similarity).
 MOD_RES 220 220 Phosphoserine (By similarity).
 MOD_RES 238 238 Phosphothreonine (By similarity).
 MOD_RES 429 429 Phosphoserine.
 MOD_RES 437 437 Phosphoserine (By similarity).
 MOD_RES 496 496 Phosphoserine (By similarity).
 MOD_RES 500 500 Phosphoserine (By similarity).
 MOD_RES 533 533 Phosphothreonine.
 MOD_RES 539 539 Phosphoserine.
 MOD_RES 568 568 Phosphoserine.
 MOD_RES 602 602 Phosphoserine.
 MOD_RES 673 673 Phosphoserine (By similarity).
 MOD_RES 692 692 Phosphoserine.
 MOD_RES 713 713 Phosphoserine (By similarity).
 MOD_RES 763 763 Phosphoserine (By similarity).
 MOD_RES 845 845 Phosphoserine (By similarity).
 MOD_RES 866 866 Phosphoserine.
 MOD_RES 871 871 Phosphoserine (By similarity).
 MOD_RES 876 876 Phosphoserine (By similarity).
 MOD_RES 887 887 Phosphoserine.
 MOD_RES 890 890 Phosphothreonine.
 MOD_RES 912 912 Phosphoserine.
 MOD_RES 974 974 Phosphoserine.
 MOD_RES 976 976 Phosphoserine (By similarity).
 MOD_RES 980 980 Phosphoserine (By similarity).
 MOD_RES 1017 1017 Phosphoserine (By similarity).
 MOD_RES 1022 1022 Phosphoserine (By similarity).
 MOD_RES 1047 1047 Phosphoserine (By similarity).
 MOD_RES 1096 1096 Phosphoserine (By similarity).
 MOD_RES 1126 1126 Phosphoserine (By similarity).
 MOD_RES 1131 1131 Phosphoserine.
 MOD_RES 1171 1171 Phosphoserine (By similarity).
 MOD_RES 1241 1241 Phosphoserine (By similarity).
 MOD_RES 1246 1246 Phosphoserine (By similarity).
 MOD_RES 1275 1275 Phosphothreonine (By similarity).
 MOD_RES 1290 1290 Phosphoserine (By similarity).
 MOD_RES 1321 1321 Phosphoserine (By similarity).
 MOD_RES 1324 1324 Phosphoserine (By similarity).
 MOD_RES 1370 1370 Phosphoserine.
 MOD_RES 1373 1373 Phosphoserine.
 MOD_RES 1375 1375 Phosphoserine.
 MOD_RES 1429 1429 Phosphoserine (By similarity).
 MOD_RES 1442 1442 Phosphoserine.
 MOD_RES 1549 1549 Phosphoserine (By similarity).
 MOD_RES 1554 1554 Phosphothreonine (By similarity).
 MOD_RES 1611 1611 Phosphoserine.
 MOD_RES 1612 1612 Phosphoserine.
 MOD_RES 1622 1622 Phosphoserine (By similarity).
 MOD_RES 1643 1643 Phosphoserine (By similarity).
 MOD_RES 1657 1657 Phosphoserine.
 MOD_RES 1706 1706 Phosphoserine (By similarity).  
Keyword
 ADP-ribosylation; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1720 AA 
Protein Sequence
MKGSTLREGT AMASPLPQDM EEELAPVGSE PGDPRAKPPV KPKPRGLPSK PALPAKPSLL 60
VPVGPRPPRG PLAELPSARK MNMLAGPQPY GVSKRPLPFA PRPSAEATAG GDVTQESGKE 120
DAGKEDLPPL TPPARCAALG GVRKAPAPFR PSSERFAACT VEEILAKMEQ PRKEILASPD 180
RLWGSRLTFN HDGSSRYGPR TYGAPCPREE DSKSPAKGRS QEGTAEIPAE CQEEHSKTPE 240
ERNLTSSPAM NGDLAKLACS EAPTDVSKTW VTSSADPVSE HGGSTSAVRL ANISVPASES 300
PRLSSRPSSP CHSQLSETQS PAASEASSIC LPVTPASPSA VLPAEPPGHS PSSELPAEAA 360
PETLSPNSSP VETVSGHHSP EQPPVLLPQL LTEGAELPDI TRTFPCGEEA AARGHTESRP 420
SSLAQRRFSE GVLQPPSQDQ EKLGGSLATL PQGQGSQSAL DRPFGSGTES NWSLSQSFEW 480
TFPTRPSGLG VWRLDSPPPS PITEASEAAE AAEADSWAVS GRGEGVSQVG PGTPPAPESP 540
RKPISGVQGN DPGISLPQRD DGESQPRSPA LLPSTVEGPP GAPLLQAKEN YEDQEPLVGH 600
ESPITLAARE AALPVLEPAL GQQQPTPSDQ PCILFVDVPD PEQALSTEED VVTLGWAETT 660
LPMTEAQEPC SVSPEPTGPE SSSRWLDDLL ASPPPNSGSA RRAAGAELKD RQSPSTCSEG 720
LLGWAQKDLQ SEFGVATDSH HSSFGSSSWS QDTSQNYSLG GRSPVGDTGL GKRDWSSKCG 780
QGSGEGSTRE WASRHSLGQE VIGIGGSQDE SEVPVRERAV GRPAQLGAQG LEADAQQWEF 840
GKRESQDPHS IHDKELQDQE FGKRDSLGSF STRDASLQDW EFGKRASVST NQDTDENDQE 900
LGMKNLSRGY SSQDAEEQDR EFEKRDSVLD IHGSRATAQQ NQEFGKSAWF QDYSSGGGGS 960
RVLGSQERGF GIRSLSSGFS PEEAQQQDEE FEKKTPVGED RFCEASRDVG HLEEGASGGL 1020
LSPSTPHSRD GAARPKDEGS WQDGDSSQEI TRLQGRMQAE SQSPTNVDLE DKEREQRGWA 1080
GEFSLGVAAQ SEAAFSPGRQ DWSRDVCVEA SESSYQFGII GNDRVSGAGL SPSRKSGGGH 1140
FVPPGETKAG AVDWTDQLGL RNLEVSSCVS SEGPSEAREN VVGQMGWSDS LGLNNGDLAR 1200
RLGTGESEEP RSLGVGEKDW TSSVEARNRD LPGQAEVGRH SQARESGVGE PDWSGAEAGE 1260
FLKSRERGVG QADWTPDLGL RNMAPGAGCS PGEPRELGVG QVDWGDDLGL RNLEVSCDLE 1320
SGGSRGCGVG QMDWAQDLGL RNLRLCGAPS EVRECGVGRV GPDLELDPKS SGSLSPGLET 1380
EDPLEARELG VGEISGPETQ GEDSSSPSFE TPSEDTGMDT GEAPSLGASP SSCLTRSPPS 1440
GSQSLLEGIM TASSSKGAPQ RESAASGSRV LLEEEGLAAG AGQGEPQEPS RAPLPSSRPQ 1500
PDGEASQVEE VDGTWSLTGA ARQNEQASAP PPRRPPRGLL PSCPSEDFSF IEDTEILDSA 1560
MYRSRANLGR KRGHRAPAIR PGGTLGLSET ADSDTRLFQD STEPRASRVP SSDEEVVEEP 1620
QSRRTRMSLG TKGLKVNLFP GLSPSALKAK LRSRNRSAEE GEVTESKSSQ KESSVQRSKS 1680
CKVPGLGKPL TLPPKPEKSS GSEGSSPNWL QALKLKKKKI 1720 
Gene Ontology
 GO:0030014; C:CCR4-NOT complex; ISS:UniProtKB.
 GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS