CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031424
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ57817, highly similar to Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
567REYIDLLKKMLTIDAubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Homeobox; Kinase; Nucleotide-binding; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1281 AA 
Protein Sequence
MTFYSWIPYH RQAPLNHRRV CSAEGAGSPG PALDPRWLPT EAHLLEAHRL LLQSVLCDRP 60
RESIQLHFRL SMASQLQVFS PPSVSSSAFC SAKKLKIEPS GWDVSGQSSN DKYYTHSKTL 120
PATQGQANSS HQVANFNIPA YDQGLLLPAP AVEHIVVTAA DSSGSAATST FQSSQTLTHR 180
SNVSLLEPYQ KCGLKRKSEE VDSNGSVQII EEHPPLMLQN RTVVGAAATT TTVTTKSSSS 240
SGEGDYQLVQ HEILCSMTNS YEVLEFLGRG TFGQVAKCWK RSTKEIVAIK ILKNHPSYAR 300
QGQIEVSILS RLSSENADEY NFVCSYECFQ HKNHTCLVFE MLEQNLYDFL KQNKFSPLPL 360
KYIRPILQQV ATALMKLKSL GLIHADLKPE NIMLVDPVRQ PYRVKVIDFG SASHVSKAVC 420
STYLQSRYYR APEIILGLPF CEAIDMWSLG CVIAELFLGW PLYPGASEYD QIRYISQTQG 480
LPAEYLLSAG TKTTRFFNRD PNLGYPLWRL KTPEEHELET GIKSKEARKY IFNCLDDMAQ 540
VNMSTDLEGT DMLAEKADRR EYIDLLKKML TIDADKRITP LKTLNHQFVT MTHLLDFPHS 600
NHVKSCFQNM EICKRRVHMY DTVSQIKSPF TTHVAPNTST NLTMSFSNQL NTVHNQASVL 660
ASSSTAAAAT LSLANSDVSL LNYQSALYPS SAAPVPGVAQ QGVSLQPGTT QICTQTDPFQ 720
QTFIVCPPAF QTGLQATTKH SGFPVRMDNA VPIVPQAPAA QPLQIQSGVL TQGSCTPLMV 780
ATLHPQVATI TPQYAVPFTL SCAAGRPALV EQTAAVLQAW PGGTQQILLP STWQQLPGVA 840
LHNSVQPTAM IPEAMGSGQQ LADWRNAHSH GNQYSTIMQQ PSLLTNHVTL ATAQPLNVGV 900
AHVVRQQQSS SLPSKKNKQS APVSSKSSLD VLPSQVYSLV GSSPLRTTSS YNSLVPVQDQ 960
HQPIIIPDTP SPPVSVITIR SDTDEEEDNK YKPSSSGLKP RSNVISYVTV NDSPDSDSSL 1020
SSPYSTDTLS ALRGNSGSVL EGPGRVVADG TGTRTIIVPP LKTQLGDCTV ATQASGLLSN 1080
KTKPVASVSG QSSGCCITPT GYRAQRGGTS AAQPLNLSQN QQSSAAPTSQ ERSSNPAPRR 1140
QQAFVAPLSQ APYTFQHGSP LHSTGHPHLA PAPAHLPSQA HLYTYAAPTS AAALGSTSSI 1200
AHLFSPQGSS RHAAAYTTHP STLVHQVPVS VGPSLLTSAS VAPAQYQHQF ATQSYIGSSR 1260
GSTIYTGYPL SPTKISQYSY L 1281 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS