UniProt Accession

 CHEV_BACSU; P37599 

Genbank Protein ID

 Z29584; U05345; AJ222587; AL009126 

Genbank Nucleotide ID

 CAA82701.1; AAA16526.1; CAA10864.1; CAB13274.1 

Protein Name

 Chemotaxis protein CheV 

Protein Synonyms/Alias

  

Gene Name

 cheV 

Gene Synonyms/Alias

 BSU14010 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
287	GADEQISKPEISDLI	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

 Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis. Moreover, CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B.subtilis chemotaxis. 

Sequence Annotation

 DOMAIN 16 154 CheW-like.
 DOMAIN 176 302 Response regulatory.
 MOD_RES 235 235 4-aspartylphosphate.  

Keyword

 Chemotaxis; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 303 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR024181; Chemotax_regulator_CheV.
 IPR002545; CheW.
 IPR011006; CheY-like_superfamily.
 IPR001789; Sig_transdc_resp-reg_receiver. 

Pfam

 PF01584; CheW
 PF00072; Response_reg 

SMART

 SM00260; CheW
 SM00448; REC 

PROSITE

 PS50851; CHEW
 PS50110; RESPONSE_REGULATORY 

PRINTS