CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA1065 protein 
Protein Synonyms/Alias
  
Gene Name
 Epn2 
Gene Synonyms/Alias
 mKIAA1065 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
125IFAIQTLKDFQYIDRubiquitination[1]
135QYIDRDGKDQGINVRubiquitination[1]
146INVREKSKQLVALLKubiquitination[1]
153KQLVALLKDEERLKVubiquitination[1]
206YSEQEYGKAGGSPASubiquitination[1]
447QPASNAGKTTDAWGAubiquitination[1]
521SLTSASSKPSSARKTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 658 AA 
Protein Sequence
GTGKFLLKGF TFVTKKIKMT TSSIRRQMKN IVNNYSEAEI KVREATSNDP WGPSSSLMTE 60
IADLTYNVVA FSEIMSMVWK RLNDHGKNWR HVYKALTLLD YLIKTGSERV AQQCRENIFA 120
IQTLKDFQYI DRDGKDQGIN VREKSKQLVA LLKDEERLKV ERVQALKTKE RMAQVATGVG 180
SNQITFGRGS SQPNLSTSYS EQEYGKAGGS PASYHGSPEA SLCPQHRTGA MLGQSEELQP 240
LSQRHPCLPH LGLASHPNGD WAQPCLTCDR AARATSPRVS SELEQARPQT SGEEELQLQL 300
ALAMSREVAE QEERLRRGDD LRLQMALEES RRDTVKVPKK KEAKACCKPG SHSQQTTLLD 360
LMDALPSSGP VTQKTEPWSA GASANQTNPW GGTVAPSNIT DPWPSFGTKP AASVDPWGVP 420
TTASTQSVPK NSDPWAASQQ PASNAGKTTD AWGAAKPSSA SGSFELFSNF NGTVKDDFSE 480
FDNLRTSKKP AESGASVPPQ DSRTTSPDLF ESQSLTSASS KPSSARKTPE SFLGPNAALV 540
NLDSLVTKPA PPAQSLNPFL APGAAAPAPV NPFQVNQPQP LTLNQLRGSP VLGSSASFGS 600
GPGVETVAPM TSVAPHSSVG ASGSSLTPLG PTAMNMVGSV GIPPSAAQST GTTNPFLL 658 
Gene Ontology
 GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
 GO:0048568; P:embryonic organ development; IGI:MGI.
 GO:0006897; P:endocytosis; IEA:InterPro.
 GO:0001701; P:in utero embryonic development; IGI:MGI.
 GO:0007219; P:Notch signaling pathway; IGI:MGI. 
Interpro
 IPR008942; ENTH_VHS.
 IPR027319; Epsin-2_metazoa.
 IPR013809; Epsin-like_N.
 IPR001026; Epsin_dom_N.
 IPR003903; Ubiquitin-int_motif. 
Pfam
 PF01417; ENTH 
SMART
 SM00273; ENTH
 SM00726; UIM 
PROSITE
 PS50942; ENTH
 PS50330; UIM 
PRINTS