UniProt Accession

 GSHB_ARATH; P46416; Q8H171; Q9SMW4; Q9SMW5 

Genbank Protein ID

 U22359; U53856; AJ243812; AJ243813; AC007123; CP002688; Z50153; X83411; AF424586; BT000624 

Genbank Nucleotide ID

 AAA64781.1; AAA99146.1; CAB51026.1; CAB51027.1; AED93678.1; CAA90515.1; CAA58318.1; AAL11580.1; AAN18190.1 

Protein Name

 Glutathione synthetase, chloroplastic 

Protein Synonyms/Alias

 GSH synthetase; GSH-S; Glutathione synthase 

Gene Name

 GSH2 

Gene Synonyms/Alias

 GSHII; At5g27380; F21A20_90 

Created Date

 July 27, 2013 

Organism

 Arabidopsis thaliana (Mouse-ear cress) 

NCBI Taxa ID

 3702 

Lysine Modification

Position	Peptide	Type	References
66	SFKMESQKPIFDLEK	acetylation	[1]

Reference

 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031] 

Functional Description

  

Sequence Annotation

 NP_BIND 428 437 ATP (By similarity).
 NP_BIND 464 467 ATP (By similarity).
 REGION 213 216 Substrate binding (By similarity).
 REGION 281 283 Substrate binding (By similarity).
 REGION 335 338 Substrate binding (By similarity).
 REGION 526 527 Substrate binding (By similarity).
 METAL 209 209 Magnesium (By similarity).
 METAL 211 211 Magnesium (By similarity).
 METAL 432 432 Magnesium (By similarity).
 BINDING 193 193 Substrate (By similarity).
 BINDING 209 209 ATP (By similarity).
 BINDING 287 287 Substrate (By similarity).
 BINDING 374 374 ATP (By similarity).
 BINDING 439 439 ATP (By similarity).
 BINDING 490 490 ATP (By similarity).
 BINDING 515 515 Substrate (By similarity).
 BINDING 517 517 ATP (By similarity).
 BINDING 523 523 ATP; via carbonyl oxygen (By similarity).  

Keyword

 ATP-binding; Chloroplast; Complete proteome; Glutathione biosynthesis; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Plastid; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 539 AA 

Protein Sequence

Gene Ontology

 GO:0009507; C:chloroplast; IDA:TAIR.
 GO:0005829; C:cytosol; IDA:TAIR.
 GO:0005524; F:ATP binding; ISS:UniProtKB.
 GO:0043295; F:glutathione binding; ISS:UniProtKB.
 GO:0004363; F:glutathione synthase activity; IDA:TAIR.
 GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
 GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
 GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR. 

Interpro

 IPR004887; Glutathione_synth_subst-bd_euk.
 IPR014042; Glutathione_synthase_a-hlx_euk.
 IPR014709; Glutathione_synthase_dom.
 IPR005615; Glutathione_synthase_euk.
 IPR014049; Glutathione_synthase_N_euk.
 IPR016185; PreATP-grasp_dom. 

Pfam

 PF03917; GSH_synth_ATP
 PF03199; GSH_synthase 

SMART

  

PROSITE

  

PRINTS