UniProt Accession

 XAGE1_HUMAN; Q9HD64; A6NJ94; Q5JPN8; Q5JPP0; Q5JPP3; Q8WWG5; Q8WWG6; Q969J6 

Genbank Protein ID

 AF251237; AJ290447; AJ400997; AJ318878; AJ318879; BT007099; AL772246; AL772246; AL772246; AL772246; AL772246; AL772246; AL772246; AL772246; BX088602; BX088602; BX088602; BX088602; BX088602; BX088602; BC009538 

Genbank Nucleotide ID

 AAG01401.1; CAC38107.1; CAC38108.1; CAC82986.1; CAC82987.1; AAP35763.1; CAI41526.1; CAI41527.1; CAI41528.1; CAI41530.1; CAI41531.1; CAI41532.1; CAI41533.1; CAI41534.1; CAI40888.1; CAI40889.1; CAI40890.1; CAI40893.1; CAI40894.1; CAI40895.1; AAH09538.2 

Protein Name

 X antigen family member 1 

Protein Synonyms/Alias

 XAGE-1; Cancer/testis antigen 12.1; CT12.1; G antigen family D member 2 

Gene Name

 XAGE1A; XAGE1B; XAGE1C; XAGE1D; XAGE1E 

Gene Synonyms/Alias

 GAGED2; XAGE1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	KKKNQQLKVGILHLG	ubiquitination	[1, 2, 3]
37	RSQCATWKVICKSCI	ubiquitination	[2]
41	ATWKVICKSCISQTP	ubiquitination	[2, 4]

Reference

 [1] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 81 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR008625; GAGE. 

Pfam

 PF05831; GAGE 

SMART

  

PROSITE

  

PRINTS