CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013028
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MPN domain-containing protein 
Protein Synonyms/Alias
  
Gene Name
 Mpnd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
457PEHTYLDKLKMSLASubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable protease (By similarity). 
Sequence Annotation
 DOMAIN 255 361 MPN.
 MOTIF 335 348 JAMM motif.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 8 8 Phosphoserine (By similarity).
 MOD_RES 168 168 Phosphoserine (By similarity).
 MOD_RES 171 171 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 487 AA 
Protein Sequence
MAAPESLSPG ATAEEAPEED EDDAEAEDPE RGTGSGGRSG SLGGSGGGTA GPGMALGGAL 60
TRRAVTLRVL LKDELLEPGE GVLSIYYLGR KFTGDLQLDG RIVWQETGQV FNSPSAWATH 120
CKKLVNPAKK SGCGWASVKY KGQKLDKYKA AWLRRHQLHM PVATADESPT SEGEEEELLL 180
EEEEEDVLAG VSSEDKGHRP PGKGSLEPEA TPPGKRMDKV PVPIRYCMLG SRDSARNPHT 240
LVEVTSFAAI NKFQPFNVAV SSNVLFLLDF HCHLTRSEVV GYLGGRWDIN NQMLTVLRAF 300
PCRSRLGDTD TAATVEEEIY QVLFLRGLSL VGWYHSHPHS PAVPSLQDID AQMEYQLRLQ 360
GSSNGFQPCL ALLCSPYYSG NPGPESKICP FWVMPPPEQR PSDYGIPMDV EMAYVQDSFL 420
TNDVLQEMVM LAEFYKGAPD LVKFQEAWSP EHTYLDKLKM SLASRTPKDQ GMCHVLEQVC 480
SVLKQGS 487 
Gene Ontology
 GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR000555; JAB1_Mov34_MPN_PAD1. 
Pfam
 PF01398; JAB 
SMART
 SM00232; JAB_MPN 
PROSITE
  
PRINTS