CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030250
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RUN and FYVE domain-containing 2 
Protein Synonyms/Alias
  
Gene Name
 Rufy2 
Gene Synonyms/Alias
 mCG_11320 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
99VRDLPGLKTPLGRARubiquitination[1]
338LAMKLLEKDIHEKQDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 606 AA 
Protein Sequence
MATKDPTAVE RANLLNMAKL SIKGLIESAL SFGRTLDSDY PPLQQFFVVM EHCLKHGLKG 60
RKSFLSYNKT IWGPLELVEK LYPEAEEIGA SVRDLPGLKT PLGRARAWLR LALMQKKMAD 120
YLRCLIIQRE LLSEFYEYHA LMMEEEGAVI VGLLVGLNVI DANLCVKGED LDSQVGVIDF 180
SMYLKNEEEI GNKERNVQIA AILDQKNYVE ELNRQLNSTV SSLHSRVDSL EKSNTKLIEE 240
LAIAKNNIIK LQEENHQLRS ENELILMRTR QHLEVTKVDV ETELQTYKHS RQGLDEMYND 300
ARRQLRDESQ LRQDVENELS VQVGMKHEME LAMKLLEKDI HEKQDTLIGL RQQLEEVKAI 360
NIEMYQRLQG SEDGLKEKNE IIARLEEKTN KITTAMRQLE QRLQQAEKAQ KEAEAEDEKY 420
AQECLSQSDS LQRQISQKEQ QLVQLETDLK IEKEWRQTLQ EDLQKEKDVL SHLRHETQKV 480
ISLKKEFLNL QDENQQLKRI YQEQEQALQE LGSKLCESKL KIDDIKEANK ALQGLVWLKD 540
KDATHCKLCE KEFSLSKRKH HCRNCGEIFC NACSDNELPL PSSPKPVRVC DSCHAMLIQR 600
CSSNMP 606 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR004012; Run.
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01363; FYVE
 PF02759; RUN 
SMART
 SM00064; FYVE
 SM00593; RUN 
PROSITE
 PS50826; RUN
 PS50178; ZF_FYVE 
PRINTS