CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041581
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Contactin 2 
Protein Synonyms/Alias
 Contactin-2 
Gene Name
 Cntn2 
Gene Synonyms/Alias
 rCG_46047 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
225STKSVFSKFAQLNLAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1040 AA 
Protein Sequence
MGTHARKKAS LLLLVLATVA LVSSPGWSFA QGTPATFGPI FEEQPIGLLF PEESAEDQVT 60
LACRARASPP ATYRWKMNGT DMNLEPGSRH QLMGGNLVIM SPTKTQDAGV YQCLASNPVG 120
TVVSKEAVLR FGFLQEFSKE ERDPVKTHEG WGVMLPCNPP AHYPGLSYRW LLNEFPNFIP 180
TDGRHFVSQT TGNLYIARTN ASDLGNYSCL ATSHMDFSTK SVFSKFAQLN LAAEDPRLFA 240
PSIKARFPPE TYALVGQQVT LECFAFGNPV PRIKWRKVDG SLSPQWATAE PTLQIPSVSF 300
EDEGTYECEA ENSKGRDTVQ GRIIVQAQPE WLKVISDTEA DIGSNLRWGC AAAGKPRPMV 360
RWLRNGEPLA SQNRVEVLAG DLRFSKLSLE DSGMYQCVAE NKHGTIYASA ELAVQALAPD 420
FRQNPVRRLI PAARGGEISI LCQPRAAPKA TILWSKGTEI LGNSTRVTVT SDGTLIIRNI 480
SRSDEGKYTC FAENFMGKAN STGILSVRDA TKITLAPSSA DINVGDNLTL QCHASHDPTM 540
DLTFTWTLDD FPIDFDKPGG HYRRASAKET IGDLTILNAQ LRHGGKYTCM AQTVVDGTSK 600
EATVLVRGPP GPPGGVVVRD IGDTTVQLSW SRGFDNHSPI AKYTLQARTP PSGKWKQVRT 660
NPVNIEGNAE TAQVLGLMPW MDYEFRVSAS NILGTGEPSG PSSKIRTKEA VPSVAPSGLS 720
GGGGAPGELI INWTPVSREY QNGDGFGYLL SFRRQGSSSW QTARVPGADA QYFVYGNDSI 780
QPYTPFEVKI RSYNRRGDGP ESLTALVYSA EEEPRVAPAK VWAKGSSSSE MNVSWEPVLQ 840
DMNGILLGYE IRYWKAGDNE AAADRVRTAG LDTSARVTGL NPNTKYHVTV RAYNRAGTGP 900
ASPSADAMTV KPPPRRPPGN ISWTFSSSSL SLKWDPVVPL RNESTVTGYK MLYQNDLHPT 960
PTLHLTSKNW IEIPVPEDIG HALVQIRTTG PGGDGIPAEV HIVRNGGTSM MVESAAARPA 1020
HPGPAFSCMV ILMLAGYQKL 1040 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0044224; C:juxtaparanode region of axon; IEA:Compara.
 GO:0043209; C:myelin sheath; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0033268; C:node of Ranvier; IEA:Compara.
 GO:0008076; C:voltage-gated potassium channel complex; IEA:Compara.
 GO:0030246; F:carbohydrate binding; IEA:Compara.
 GO:0007628; P:adult walking behavior; IEA:Compara.
 GO:0007411; P:axon guidance; IEA:Compara.
 GO:0007413; P:axonal fasciculation; IEA:Compara.
 GO:0022010; P:central nervous system myelination; IEA:Compara.
 GO:0021853; P:cerebral cortex GABAergic interneuron migration; IEA:Compara.
 GO:0045163; P:clustering of voltage-gated potassium channels; IEA:Compara.
 GO:0071206; P:establishment of protein localization to juxtaparanode region of axon; IEA:Compara.
 GO:0007612; P:learning; IEA:Compara.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:Compara.
 GO:0045665; P:negative regulation of neuron differentiation; IEA:Compara.
 GO:0001764; P:neuron migration; IEA:Compara.
 GO:0060168; P:positive regulation of adenosine receptor signaling pathway; IEA:Compara.
 GO:0010954; P:positive regulation of protein processing; IEA:Compara.
 GO:0031623; P:receptor internalization; IEA:Compara.
 GO:0048710; P:regulation of astrocyte differentiation; IEA:Compara.
 GO:0031133; P:regulation of axon diameter; IEA:Compara.
 GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Compara. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 
Pfam
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00409; IG
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS