UniProt Accession

 A2IDA3_HUMAN; A2IDA3 

Genbank Protein ID

 Z69720 

Genbank Nucleotide ID

 CAM26663.1 

Protein Name

 DNA-3-methyladenine glycosylase 

Protein Synonyms/Alias

 N-methylpurine-DNA glycosylase 

Gene Name

 MPG 

Gene Synonyms/Alias

 Z69720.1-004 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
63	SIYFSSPKGHLTRLG	ubiquitination	[1, 2]
212	CQALAINKSFDQRDL	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 251 AA 

Protein Sequence

Gene Ontology

 GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006284; P:base-excision repair; IEA:Compara. 

Interpro

 IPR011034; Formyl_transferase_C-like.
 IPR003180; PurDNA_glycsylse. 

Pfam

 PF02245; Pur_DNA_glyco 

SMART

  

PROSITE

  

PRINTS