CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038059
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dgkd 
Protein Synonyms/Alias
  
Gene Name
 Dgkd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
512KVLCETVKDFVARVGubiquitination[1]
720SLPALNTKILYPSVRubiquitination[1]
1020HAVNASSKAMERVYGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1220 AA 
Protein Sequence
MAAAAGAPPP GPPQPPPPPP PEESSDSEPE AEPGSPQKLI RKVSTSGQIR QKTILKEGML 60
TKQNNSFQRS KRRYFKLRGR TLYYAKTAKS IIFDEVDLTD ASVAESSTKN VNNSFTVITP 120
CRKLILCADN RKEMEDWIAA LKTVQNKEHF EPTQYSMDHF SGMHNWYACS HARPTYCNVC 180
REVLSGVTSH GLSCEVCKFK AHKRCAVRAT SNCKWTTLAS IGKDIIEDED GIAMPHQWLE 240
GNLPVSAKCI VCDKTCGSVL RLQDWRCLWC KAMVHTSCKE SLVMKCPLGL CKVSVIPPTA 300
LNSIDSDGFW KATCPPSCTS PLLVFVNSKS GDNQGVKFLR RFKQLLNPAQ VFDLMNGGPH 360
LGLRLFQKFD TFRILVCGGD GSVGWVLSEI DSLNLHKQCQ LGVLPLGTGN DLARVLGWGS 420
ACDDDTQLPQ ILAKLERAST KMLDRWSVMA YETKLPRQAS SSTVTEDFSE DSEVQQILFY 480
EDSVAAHLSK ILTSDQHSVV ISSAKVLCET VKDFVARVGK AYEKTTESSQ ESEVMAKKCS 540
VLKEKLDSLL KTLDDESQAS SSLSNPPPTI AEEAEDGDGS GNICSSTGDH LVGSACPSRP 600
QIFRPREQLM LRANSLKKAI RQIIEHTEKA VDEQNAQTQE QQGFVLGLSE SEKKDLKTDN 660
RVCTSSVHSE SCVIAKGRSQ RKASRAPCEK LVSKGLSLGS SASLPPGTGS RDSLPALNTK 720
ILYPSVRAGM SGSLPGGSVI SRLLINADPF NAEPENLEYY TEKCVMNNYF GIGLDAKISL 780
DFNNKRDEHP EKCRSRTKNM MWYGVLGTKE LLHRTYRNLE QKVLLECDGR PIPLPSLQGI 840
AVLNIPSYAG GTNFWGGTKE DDTFAAPSFD DKILEVVAVF GSMQMAVSRV IKLQHHRIAQ 900
CRTVKISILG DEGVPVQVDG EAWIQPPGYI RIVHKNRAQT LTRDRAFENT LKSWEDKQKC 960
ELSRPPSFSL HPEILSEEEA TQMDQFGQAA GGLIHSIREI AQSHRAMEQE LAHAVNASSK 1020
AMERVYGKPR TAEGLNCSFV LEMVNNIRAL RSETELLLAG KMALQLDPPQ KERLGAALIE 1080
MDQQLRKLTD TPWLCQPLEP GEEESLQQNV MLDLTKRSRS GKFRLVTKFK KEKNNKNKEV 1140
HSNLGGPVHL WGTEEVAAWL EHLSLCEYKD IFTRHDIRGS ELLHLERRDL KDLGVTKVGH 1200
MKRILCGIKE LSRSSPAAEA 1220 
Gene Ontology
 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004143; F:diacylglycerol kinase activity; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0051260; P:protein homooligomerization; IEA:Compara.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0010033; P:response to organic substance; IEA:Compara. 
Interpro
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR011510; SAM_2. 
Pfam
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat
 PF00169; PH
 PF07647; SAM_2 
SMART
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc
 SM00233; PH
 SM00454; SAM 
PROSITE
 PS50146; DAGK
 PS50003; PH_DOMAIN
 PS50105; SAM_DOMAIN
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS