UniProt Accession

 ARM10_HUMAN; Q8N2F6; A8K703; B4DWJ8; F5GX65; Q75K91; Q75MG6; Q75ML8; Q8IZC1; Q8IZC2; Q8IZC3; Q9BTM6 

Genbank Protein ID

 AY150851; AY150852; AY150853; AY150854; AK075500; AK291818; AK301565; AC007683; AC073127; AC108167; BC003586 

Genbank Nucleotide ID

 AAN72313.1; AAN72314.1; AAN72315.1; AAN72316.1; BAC11655.1; BAF84507.1; BAG63060.1; AAS07531.1; AAS07482.1; AAS07456.1; AAH03586.1 

Protein Name

 Armadillo repeat-containing protein 10 

Protein Synonyms/Alias

 Splicing variant involved in hepatocarcinogenesis protein 

Gene Name

 ARMC10 

Gene Synonyms/Alias

 SVH; PSEC0198 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
44	ELGIRSSKSAEDLTD	ubiquitination	[1, 2]
239	LYDSHVAKEILLRVL	ubiquitination	[2]
300	HDAEVKEKVVTIIPK	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53. 

Sequence Annotation

 REPEAT 138 180 ARM.
 MOD_RES 45 45 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Growth regulation; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 343 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. 

Interpro

 IPR011989; ARM-like.
 IPR006911; ARM-rpt_dom.
 IPR016024; ARM-type_fold. 

Pfam

 PF04826; Arm_2 

SMART

  

PROSITE

 PS50176; ARM_REPEAT 

PRINTS