CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045402
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ER lumen protein retaining receptor 
Protein Synonyms/Alias
  
Gene Name
 KDELR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
83WLIYSKFKATYDGNHubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; Membrane; Protein transport; Receptor; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MNLFRFLGDL SHLLAIILLL LKIWKSRSCA GISGKSQVLF AVVFTARYLD LFTNYISLYN 60
TCMKVVYIAC SFTTVWLIYS KFKATYDGNH DTFRVEFLVV PTAILAFLVN HDFTPLEEDR 120
PGWPDVLIFS TEAIIQEFSD PLDLLHLPGV SGHLAAAVHG EQDRRGGDHH QPLLVCARRL 180
PHALSLQLDL ALPFRGLLRP HRHCGRPGPD SPLLRFLLPL 220 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0046923; F:ER retention sequence binding; IEA:InterPro.
 GO:0006621; P:protein retention in ER lumen; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR000133; ER_ret_rcpt. 
Pfam
 PF00810; ER_lumen_recept 
SMART
  
PROSITE
 PS00951; ER_LUMEN_RECEPTOR_1 
PRINTS
 PR00660; ERLUMENR.