Tag | Content |
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CPLM ID | CPLM-022624 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inositol oxygenase |
Protein Synonyms/Alias | Aldehyde reductase-like 6; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductase |
Gene Name | Miox |
Gene Synonyms/Alias | Aldrl6; Rsor |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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2 | ******MKVDVGPDP | ubiquitination | [1] | 23 | DVDPEMAKSKDSFRN | ubiquitination | [1] | 206 | YQMMKFNKFSLPSEA | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | REGION 85 88 Substrate binding. REGION 141 142 Substrate binding. REGION 220 221 Substrate binding. METAL 98 98 Iron 1. METAL 123 123 Iron 1. METAL 124 124 Iron 1. METAL 124 124 Iron 2. METAL 194 194 Iron 2. METAL 220 220 Iron 2. METAL 253 253 Iron 1. BINDING 29 29 Substrate. BINDING 127 127 Substrate. |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Iron; Metal-binding; Oxidoreductase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 285 AA |
Protein Sequence | MKVDVGPDPS LVYRPDVDPE MAKSKDSFRN YTSGPLLDRV FTTYKLMHTH QTVDFVSRKR 60 IQYGSFSYKK MTIMEAVGML DDLVDESDPD VDFPNSFHAF QTAEGIRKAH PDKDWFHLVG 120 LLHDLGKIMA LWGEPQWAVV GDTFPVGCRP QASVVFCDST FQDNPDLQDP RYSTELGMYQ 180 PHCGLENVLM SWGHDEYLYQ MMKFNKFSLP SEAFYMIRFH SFYPWHTGGD YRQLCSQQDL 240 DMLPWVQEFN KFDLYTKCPD LPDVESLRPY YQGLIDKYCP GTLSW 285 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0016234; C:inclusion body; ISS:UniProtKB. GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB. GO:0008199; F:ferric iron binding; ISS:UniProtKB. GO:0050113; F:inositol oxygenase activity; ISS:UniProtKB. GO:0050661; F:NADP binding; IEA:Compara. GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IDA:UniProtKB. GO:0019310; P:inositol catabolic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |