CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SDHA protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
372ELRLSMQKSMQNHAAubiquitination[1]
463IDEYDYSKPIQGQQKubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 519 AA 
Protein Sequence
MSGVRGLSRL LSARRLALAK AWPTVLQTGT RGFHFTVDGN KRASAKVSDS ISAQYPVVDH 60
EFDAVVVGAG GAGLRAAFGL SEAGFNTACV TKLFPTRSHT VAAQGGINAA LGNMEEDNWR 120
WHFYDTSTGD GTAMITRAGL PCQDLEFVQF HPTGIYGAGC LITEGCRGEG GILINSQGER 180
FMERYAPVAK DLASRDVVSR SMTLEIREGR GCGPEKDHVY LQLHHLPPEQ LATRLPGISE 240
TAMIFAGVDV TKEPIPVLPT VHYNMGGIPT NYKGQVLRHV NGQDQIVPGL YACGEAACAS 300
VHGANRLGAN SLLDLVVFGR ACALSIEESC RPGDKVPPIK PNAGEESVMN LDKLRFADGS 360
IRTSELRLSM QKSMQNHAAV FRVGSVLQEG CGKISKLYGD LKHLKTFDRG MVWNTDLVET 420
LELQNLMLCA LQTIYGAEAR KESRGAHARE DYKVRIDEYD YSKPIQGQQK KPFEEHWRKH 480
TLSFVDVGTG KVTLEYRPVI DKTLNEADCA TVPPAIRSY 519 
Gene Ontology
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:InterPro. 
Interpro
 IPR003953; FAD_bind_dom.
 IPR003952; FRD_SDH_FAD_BS.
 IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
 IPR027477; Succ_DH/fumarate_Rdtase_cat.
 IPR014006; Succ_Dhase_FrdA_Gneg. 
Pfam
 PF00890; FAD_binding_2
 PF02910; Succ_DH_flav_C 
SMART
  
PROSITE
 PS00504; FRD_SDH_FAD_BINDING 
PRINTS