UniProt Accession

 Q5TDE9_HUMAN; Q5TDE9 

Genbank Protein ID

 AK316591; CH471098 

Genbank Nucleotide ID

 BAG38178.1; EAW69979.1 

Protein Name

 Chromosome 1 open reading frame 57, isoform CRA_d 

Protein Synonyms/Alias

 cDNA, FLJ95865 

Gene Name

 C1orf57 

Gene Synonyms/Alias

 hCG_15829 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
21	GKTTLIHKASEVLKS	ubiquitination	[1]
73	GLEPPPGKRECRVGQ	ubiquitination	[2]
148	LGTIPVPKGKPLALV	ubiquitination	[1]
150	TIPVPKGKPLALVEE	ubiquitination	[2]
165	IRNRKDVKVFNVTKE	ubiquitination	[1]
171	VKVFNVTKENRNHLL	ubiquitination	[1, 2]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Nucleotide-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 190 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0019204; F:nucleotide phosphatase activity; IEA:InterPro.
 GO:0016740; F:transferase activity; IEA:InterPro. 

Interpro

 IPR003593; AAA+_ATPase.
 IPR004948; Nuc-triphosphatase_THEP1.
 IPR027417; P-loop_NTPase. 

Pfam

 PF03266; NTPase_1 

SMART

 SM00382; AAA 

PROSITE

  

PRINTS