CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034654
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BRCA2 and CDKN1A-interacting protein 
Protein Synonyms/Alias
  
Gene Name
 Bccip 
Gene Synonyms/Alias
 Bccip_predicted; rCG_48513 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
175KLLNDTSKPVGLLLSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ) (By similarity). 
Sequence Annotation
  
Keyword
 Cell cycle; Complete proteome; DNA damage; DNA repair; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 315 AA 
Protein Sequence
MASKAKKRAV GNGVQRPLEA PSQREEEEED ELEDEEEDDE DSEEEEDDED DEIVDEEVNI 60
EFEAYSISDN DYGGIKKLLQ QLFLKAPVNT AELANLLIQQ NHIGSVIKQT DVSEDSDGEV 120
DEDEIFGFIS LLNLSERKGT QCAEQIKELV LSSCEKSCEQ SMVEQLDKLL NDTSKPVGLL 180
LSERFINVPP QIALPMHQQL QKELAEARRT NKPCGKCCFY LLISKTFVEA GKSTSRKRRD 240
GLPQEALMFA NAEEEFFYEK AVLKFSYSVQ GESDTCLGGR WSFDDVPMKP LRTVMLIPDD 300
KMSEIMETLK DHLSI 315 
Gene Ontology
 GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IEA:Compara.
 GO:0019207; F:kinase regulator activity; IEA:Compara.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
 GO:0061101; P:neuroendocrine cell differentiation; IEA:Compara.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Compara. 
Interpro
 IPR025602; BCP1_family. 
Pfam
 PF13862; BCIP 
SMART
  
PROSITE
  
PRINTS