CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein YIPF3 
Protein Synonyms/Alias
 Killer lineage protein 1; Natural killer cell-specific antigen KLIP1; YIP1 family member 3; Protein YIPF3, 36 kDa form III 
Gene Name
 YIPF3 
Gene Synonyms/Alias
 C6orf109; KLIP1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
83DGEFLGMKGFKGQLSubiquitination[1, 2]
86FLGMKGFKGQLSRQVubiquitination[1, 2, 3, 4, 5]
102DQMWQAGKRQASRAFubiquitination[1, 2, 3, 4, 5, 6]
141LESMIPIKMVNFPQKubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [6] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572] 
Functional Description
 Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis. 
Sequence Annotation
 CARBOHYD 333 333 O-linked (GalNAc...).
 CARBOHYD 334 334 O-linked (GalNAc...).
 CARBOHYD 337 337 N-linked (GlcNAc...).
 CARBOHYD 339 339 O-linked (GalNAc...).
 CARBOHYD 346 346 O-linked (GalNAc...).  
Keyword
 Cell membrane; Complete proteome; Cytoplasm; Differentiation; Glycoprotein; Golgi apparatus; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MATTAAPAGG ARNGAGPEWG GFEENIQGGG SAVIDMENMD DTSGSSFEDM GELHQRLREE 60
EVDADAADAA AAEEEDGEFL GMKGFKGQLS RQVADQMWQA GKRQASRAFS LYANIDILRP 120
YFDVEPAQVR SRLLESMIPI KMVNFPQKIA GELYGPLMLV FTLVAILLHG MKTSDTIIRE 180
GTLMGTAIGT CFGYWLGVSS FIYFLAYLCN AQITMLQMLA LLGYGLFGHC IVLFITYNIH 240
LHALFYLFWL LVGGLSTLRM VAVLVSRTVG PTQRLLLCGT LAALHMLFLL YLHFAYHKVV 300
EGILDTLEGP NIPPIQRVPR DIPAMLPAAR LPTTVLNATA KAVAVTLQSH 350 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0030133; C:transport vesicle; IDA:LIFEdb.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. 
Interpro
 IPR026637; YIPF3. 
Pfam
  
SMART
  
PROSITE
  
PRINTS