| Tag | Content |
|---|
| CPLM ID | CPLM-003956 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NADH-ubiquinone oxidoreductase chain 5 |
Protein Synonyms/Alias | NADH dehydrogenase subunit 5 |
Gene Name | Mtnd5 |
Gene Synonyms/Alias | mt-Nd5; Nd5 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 455 | PNLINPIKRLALGSI | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix; Transport; Ubiquinone. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 610 AA |
Protein Sequence | MNMMTILILM ILDLLTTPIT FSMTILTKLM YFRHMLITSI KFSFLLSLLP LLLFFHHNTE 60
YMITNWHWLT INSIKLTMSF KIDYFSILFL SVSLFVTWSI MQFSSWYMHS DPHINRFIKY 120
LMMFLNNMLI LTSANNLFQL FIGWEGVGIM SFLLIGWWYG LADANTAALQ AILYNRVGDI 180
GFILAMTWFC LNMNSWELQQ IFLTNTNNNL VPLTGLLIAA TGKSAQFGLH PWLPSAMEGP 240
TPVSALLHSS TMVVAGIFLM IRFHPLTSNN STIMTAMLCL GAITTLFTAI CALTQNDIKK 300
IVAFSTSSQL GLMMVTLGIN QPYLAFLHIC THAFFKAMLF MCSGSIIHIL NDEQDIRKMG 360
NMMKAMPFTS SCLIIGSLAL TGMPFLTGFY SKDLIIEAIN TCNTNAWALM ITLIATSMTA 420
VYSMRIIYFV TMTKPRYSPL ITINENNPNL INPIKRLALG SILAGFLISL NIPPTNIQIL 480
TMPWHLKMTA LLITILGFAI ALELNNLTLN LSMSKPTKLS SFSTSLGYYP PIMPRIIPQK 540
TLNSSYKLSL NLLDLIWSEK TIPKSTSITQ TQLSKMMSNQ KGLIKLYFLS FLITISLIFI 600
LHTLNPEWFQ 610 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0043005; C:neuron projection; IDA:RGD. GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC. GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro. GO:0042542; P:response to hydrogen peroxide; IEP:RGD. GO:0001666; P:response to hypoxia; IEP:RGD. GO:0010243; P:response to organic nitrogen; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |