CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021370
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1 
Protein Synonyms/Alias
 t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1 
Gene Name
 OSGEPL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
230KAIEHLAKQGNRFHFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). 
Sequence Annotation
 MOD_RES 7 7 Phosphothreonine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MLILTKTAGV FFKPSKRKVY EFLRSFNFHP GTLFLHKIVL GIETSCDDTA AAVVDETGNV 60
LGEAIHSQTE VHLKTGGIVP PAAQQLHREN IQRIVQEALS ASGVSPSDLS AIATTIKPGL 120
ALSLGVGLSF SLQLVGQLKK PFIPIHHMEA HALTIRLTNK VEFPFLVLLI SGGHCLLALV 180
QGVSDFLLLG KSLDIAPGDM LDKVARRLSL IKHPECSTMS GGKAIEHLAK QGNRFHFDIK 240
PPLHHAKNCD FSFTGLQHVT DKIIMKKEKE EGIEKGQILS SAADIAATVQ HTMACHLVKR 300
THRAILFCKQ RDLLPQNNAV LVASGGVASN FYIRRALEIL TNATQCTLLC PPPRLCTDNG 360
IMIAWNGIER LRAGLGILHD IEGIRYEPKC PLGVDISKEV GEASIKVPQL KMEI 414 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR000905; Gcp-like_dom.
 IPR017861; KAE1/YgjD. 
Pfam
 PF00814; Peptidase_M22 
SMART
  
PROSITE
  
PRINTS
 PR00789; OSIALOPTASE.