UniProt Accession

 CYC2_DROME; P84029; P00033; P00034; Q9VJJ3 

Genbank Protein ID

 X01760; M11381; AE014134; AY071701 

Genbank Nucleotide ID

 CAA25900.1; AAA28437.1; AAF53554.1; AAL49323.1 

Protein Name

 Cytochrome c-2 

Protein Synonyms/Alias

 Cytochrome c-proximal 

Gene Name

 Cyt-c-p 

Gene Synonyms/Alias

 CYTC2; DC4; CG17903 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
10	VPAGDVEKGKKLFVQ	acetylation	[1]
104	GDLIAYLKSATK***	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. 

Sequence Annotation

 METAL 23 23 Iron (heme axial ligand).
 METAL 85 85 Iron (heme axial ligand).
 BINDING 19 19 Heme (covalent).
 BINDING 22 22 Heme (covalent).  

Keyword

 Complete proteome; Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Mitochondrion; Reference proteome; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 108 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; ISS:FlyBase.
 GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IDA:FlyBase.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
 GO:0006119; P:oxidative phosphorylation; ISS:FlyBase. 

Interpro

 IPR002327; Cyt_c_1A/1B.
 IPR009056; Cyt_c_dom.
 IPR003088; Cyt_c_I. 

Pfam

 PF00034; Cytochrom_C 

SMART

  

PROSITE

 PS51007; CYTC 

PRINTS

 PR00604; CYTCHRMECIAB.