UniProt Accession

 C9J4G7_HUMAN; C9J4G7 

Genbank Protein ID

 AC004859; AC011894 

Genbank Nucleotide ID

  

Protein Name

 2-oxoglutarate dehydrogenase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 OGDH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
74	ENPKSVHKSWDIFFR	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 211 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:Compara.
 GO:0034602; F:oxoglutarate dehydrogenase (NAD+) activity; IEA:Compara.
 GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
 GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
 GO:0006103; P:2-oxoglutarate metabolic process; IEA:Compara.
 GO:0021695; P:cerebellar cortex development; IEA:Compara.
 GO:0021766; P:hippocampus development; IEA:Compara.
 GO:0006734; P:NADH metabolic process; IEA:Compara.
 GO:0061034; P:olfactory bulb mitral cell layer development; IEA:Compara.
 GO:0021860; P:pyramidal neuron development; IEA:Compara.
 GO:0021756; P:striatum development; IEA:Compara.
 GO:0006104; P:succinyl-CoA metabolic process; IEA:Compara.
 GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IEA:Compara.
 GO:0021794; P:thalamus development; IEA:Compara.
 GO:0006099; P:tricarboxylic acid cycle; IEA:Compara. 

Interpro

 IPR011603; 2oxoglutarate_DH_E1. 

Pfam

  

SMART

  

PROSITE

  

PRINTS