CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029026
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Par-3 (Partitioning defective 3) homolog (C. elegans) 
Protein Synonyms/Alias
 Partitioning defective 3 homolog 
Gene Name
 Pard3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
181STTAGFLKQNTAGSPubiquitination[1]
235MVDRWLEKQEQDEEGubiquitination[1]
567PSQMQTPKETKAEDEubiquitination[1]
611SVKGNRSKENHADLGubiquitination[1]
622ADLGIFVKSIINGGAacetylation[2]
632INGGAASKDGRLRVNubiquitination[1]
831SMSEKRTKQFSDASQubiquitination[1]
843ASQLDFVKTRKSKSMubiquitination[1]
859LGIADETKLNTVDDQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1334 AA 
Protein Sequence
MKVTVCFGRT RVVVPCGDGR MKVFSLIQQA VTRYRKAVAK DPNYWIQVHR LEHGDGGILD 60
LDDILCDVAD DKDRLVAVFD EQDPHHGGDG TSASSTGTQS PEIFGSELGT NNVSAFQPYQ 120
ATSEIEVTPS VLRANMPLHV RRSSDPALTG LSTSVSDNNF SSEEPSRKNP TRWSTTAGFL 180
KQNTAGSPKT CDRKKDENYR SLPRDPSSWS NQFQRDNARS SLSASHPMVD RWLEKQEQDE 240
EGTEEDSSRV EPVGHADTGL ENMPNFSLDD MVKLVQVPND GGPLGIHVVP FSARGGRTLG 300
LLVKRLEKGG KAEQENLFHE NDCIVRINDG DLRNRRFEQA QHMFRQAMRA RVIWFHVVPA 360
ANKEQYEQLS QREKNNYSPG RFSPDSHCVA NRSVANNAPQ ALPRAPRLSQ PPEQLDAHPR 420
LPHSAHASTK PPAAPALAPP SVLSTNVGSV YNTKKVGKRL NIQLKKGTEG LGFSITSRDV 480
TIGGSAPIYV KNILPRGAAI QDGRLKAGDR LIEVNGVDLA GKSQEEVVSL LRSTKMEGTV 540
SLLVFRQEEA FHPREMNAEP SQMQTPKETK AEDEDVVLTP DGTREFLTFE VPLNDSGSAG 600
LGVSVKGNRS KENHADLGIF VKSIINGGAA SKDGRLRVND QLIAVNGESL LGKANQEAME 660
TLRRSMSTEG NKRGMIQLIV ARRISRCNEL RSPGSPAAPE LPIETELDDR ERRISHSLYS 720
GIEGLDESPT RNAALSRIMG KCQLSPTVNM PHDDTVMIED DRLPVLPPHL SDQSSSSSHD 780
DVGFIMTEAG TWAKATISDS ADCSLSPDVD PVLAFQREGF GRQSMSEKRT KQFSDASQLD 840
FVKTRKSKSM DLGIADETKL NTVDDQRAGS PSRDVGPSLG LKKSSSLESL QTAVAEVTLN 900
GNIPFHRPRP RIIRGRGCNE SFRAAIDKSY DKPMVDDDDE GMETLEEDTE ESSRSGRESV 960
STSSDQPSYS LERQMNGDPE KRDKTERKKD KAGKDKKKDR EKEKDKLKAK KGMLKGLGDM 1020
FRFGKHRKDD KMEKMGRIKI QDSFTSEEDR VRMKEEQERI QAKTREFRER QARERDYAEI 1080
QDFHRTFGCD DELLYGGMSS YEGCLALNAR PQSPREGHLM DTLYAQVKKP RSSKPGDSNR 1140
STPSNHDRIQ RLRQEFQQAK QDEDVEDRRR TYSFEQSWSS SRPASQSGRH SVSVEVQVQR 1200
QRQEERESFQ QAQRQYSSLP RQSRKNASSI SQDSWEQNYA PGEGFQSAKE NPRYSSYQGS 1260
RNGYLGGHGF NARVMLETQE LLRQEQRRKE QQLKKQPPAD GVRGPFRQDV PPSPSQVARL 1320
NRLQTPEKGR PFYS 1334 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:MGI.
 GO:0005938; C:cell cortex; IDA:MGI.
 GO:0005913; C:cell-cell adherens junction; IDA:MGI.
 GO:0005819; C:spindle; IDA:MGI.
 GO:0003383; P:apical constriction; IGI:MGI.
 GO:0016337; P:cell-cell adhesion; IC:MGI.
 GO:0051642; P:centrosome localization; IMP:MGI.
 GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.
 GO:0032970; P:regulation of actin filament-based process; IGI:MGI.
 GO:0044319; P:wound healing, spreading of cells; IMP:MGI. 
Interpro
 IPR021922; DUF3534.
 IPR001478; PDZ. 
Pfam
 PF12053; DUF3534
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS50106; PDZ 
PRINTS