UniProt Accession

 MHR1_YEAST; Q06630; D6VSS5 

Genbank Protein ID

 AB016430; U28374; AY557735; BK006938 

Genbank Nucleotide ID

 BAA88081.1; AAB64732.1; AAS56061.1; DAA12135.1 

Protein Name

 Mitochondrial homologous recombination protein 1 

Protein Synonyms/Alias

 Cross-linked transcription component 1 

Gene Name

 MHR1 

Gene Synonyms/Alias

 XTC1; YDR296W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
153	ENATPAEKQTVPAKK	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells. 

Sequence Annotation

  

Keyword

 Complete proteome; Direct protein sequencing; Mitochondrion; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000150; F:recombinase activity; IMP:SGD.
 GO:0003697; F:single-stranded DNA binding; IDA:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
 GO:0000002; P:mitochondrial genome maintenance; IDA:SGD.
 GO:0090297; P:positive regulation of mitochondrial DNA replication; IMP:SGD.
 GO:0006355; P:regulation of transcription, DNA-dependent; IPI:SGD.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR024629; Mhr1. 

Pfam

 PF12829; Mhr1 

SMART

  

PROSITE

  

PRINTS