CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035744
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptojanin-1 
Protein Synonyms/Alias
  
Gene Name
 Synj1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
5***MAFSKGFRIYHKacetylation[1]
295TLKDLYGKQIVVNLLacetylation[1]
305VVNLLGSKEGEHMLSacetylation[1]
352EKLHSVLKPQVQKFLacetylation[1]
414EALGLAEKPQLVTRFacetylation[1]
577GIQEFQDKRSKPTDIubiquitination[2]
659DVAVDTVKTGMGGATubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1574 AA 
Protein Sequence
MAFSKGFRIY HKLDPPPFSL IVETRHKEEC LMFESGAVAV LSSAEKEAIK GTYAKVLDAY 60
GLLGVLRLNL GDTMLHYLVL VTGCMSVGKI QESEVFRVTS TEFISLRVDA SDEDRISEVR 120
KVLNSGNFYF AWSASGVSLD LSLNAHRSMQ EHTTDNRFFW NQSLHLHLKH YGVNCDDWLL 180
RLMCGGVEIR TIYAAHKQAK ACLISRLSCE RAGTRFNVRG TNDDGHVANF VETEQVIYLD 240
DCVSSFIQIR GSVPLFWEQP GLQVGSHRVR MSRGFEANAP AFDRHFRTLK DLYGKQIVVN 300
LLGSKEGEHM LSKAFQSHLK ASEHASDIHM VSFDYHQMVK GGKAEKLHSV LKPQVQKFLD 360
YGFFYFDGSA VQRCQSGTVR TNCLDCLDRT NSVQAFLGLE MLAKQLEALG LAEKPQLVTR 420
FQEVFRSMWS VNGDSISKIY AGTGALEGKA KLKDGARSVT RTIQNNFFDS SKQEAIDVLL 480
LGNTLNSDLA DKARALLTTG SLRGSHCSQA ASSSKVLKNM CENFYKYSKP KKIRVCVGTW 540
NVNGGKQFRS IAFKNQTLTD WLLDAPKLAG IQEFQDKRSK PTDIFAIGFE EMVELNAGNI 600
VNASTTNQKL WAVELQKTIS RDNKYVLLAS EQLVGVCLFV FIRPQHAPFI RDVAVDTVKT 660
GMGGATGNKG AVAIRMLFHT TSLCFVCSHF AAGQSQVKER NEDFVEIARK LSFPMGRMLF 720
SHDYVFWCGD FNYRIDLPNE EVKELIRQQN WDSLIAGDQL INQKNAGQIF RGFLEGKVTF 780
APTYKYDLFS EDYDTSEKCR TPAWTDRVLW RRRKWPFDRS AEDLDLLNAS FQDESKILYT 840
WTPGTLLHYG RAELKTSDHR PVVALIDIDI FEVEAEERQK IYKEVIAVQG PPDGTVLVSI 900
KSSAQENTFF DDALIDELLQ QFAHFGEVIL IRFVEDKMWV TFLEGSSALN VLSLNGKELL 960
NRTITITLKS PDWIKTLEEE MSLEKISVTL PSSTSSTLLG EDAEVSADFD MEGDVDDYSA 1020
EVEELLPQHL QPSSSSGLGT SPSSSPRTSP CQSPTAPEYS APSLPIRPSR APSRTPGPLS 1080
SQGAPVDTQP AAQKESSQTI EPKRPPPPRP VAPPARPAPP QRPPPPSGAR SPAPARKEFG 1140
GVGAPPSPGV TRREMEAPKS PGTARKDNIG RNQPSPQAGL AGPGPSGYGA ARPTIPARAG 1200
VISAPQSQAR VSAGRLTPES QSKPLETSKG PAVLPEPLKP QAAFPPQPSL PTPAQKLQDP 1260
LVPIAAPMPP SIPQSNLETP PLPPPRSRSS QSLPSDSSPQ LQHQSKNSIQ VKINGACGVK 1320
QEPTLKSDPF EDLSLSVLAV SKAQPSAQIS PVLTPDPKML IQLPSASQSK VNSLSSVSCM 1380
LTMPPVPEQS KSQESVGSSA NPFPSLPTRN PFTDRTAAPG NPFRVQSQES EATSWLSKEE 1440
PVSNSPFPPL MPLSHDMSKP SSSLDGFEDN FDLQSQSTVK TSNPKGWVTF DEDEDFPTKG 1500
KSRSVYPDSL GNTAASFDDD WSKGTNVSFC VLPARRPPPP PPPVPLLPPG TTSSAGPSTT 1560
LSSKASPTLD FTER 1574 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
 GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro. 
Interpro
 IPR015047; DUF1866.
 IPR005135; Endo/exonuclease/phosphatase.
 IPR000300; IPPc.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR002013; Syja_N. 
Pfam
 PF08952; DUF1866
 PF03372; Exo_endo_phos
 PF02383; Syja_N 
SMART
 SM00128; IPPc 
PROSITE
 PS50102; RRM
 PS50275; SAC 
PRINTS