CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037500
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cathepsin W 
Protein Synonyms/Alias
  
Gene Name
 CTSW 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39GPQPLELKEAFKLFQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 364 AA 
Protein Sequence
MALTAHPSCL LALLVAGLAQ GIRGPLRAQD LGPQPLELKE AFKLFQIQFN RSYLSPEEHA 60
HRLDIFAHNL AQAQRLQEED LGTAEFGVTP FSDLTEEEFG QLYGYRRAAG GVPSMGREIR 120
SEEPEESVPF SCDWRKVASA ISPIKDQKNC NCCWAMAAAG NIETLWRISF WDFVDVSVQE 180
LLDCGRCGDG CHGGFVWDAF ITVLNNSGLA SEKDYPFQGK VRAHRCHPKK YQKVAWIQDF 240
IMLQNNEHRI AQYLATYGPI TVTINMKPLQ LYRKGVIKAT PTTCDPQLVD HSVLLVGFGS 300
VKSEEGIWAE TVSSQSQPQP PHPTPYWILK NSWGAQWGEK VSVIYWGRGQ GRTGLFPPSR 360
PYVP 364 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR025660; Pept_his_AS.
 IPR013128; Peptidase_C1A.
 IPR000668; Peptidase_C1A_C.
 IPR013201; Prot_inhib_I29. 
Pfam
 PF08246; Inhibitor_I29
 PF00112; Peptidase_C1 
SMART
 SM00848; Inhibitor_I29
 SM00645; Pept_C1 
PROSITE
 PS00639; THIOL_PROTEASE_HIS 
PRINTS
 PR00705; PAPAIN.