CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007404
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Surface presentation of antigens protein SpaS 
Protein Synonyms/Alias
  
Gene Name
 spaS 
Gene Synonyms/Alias
 STM2887 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
230QEGNPEVKSKRREVHacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells. 
Sequence Annotation
  
Keyword
 3D-structure; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Virulence. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MSSNKTEKPT KKRLEDSAKK GQSFKSKDLI IACLTLGGIA YLVSYGSFNE FMGIIKIIIA 60
DNFDQSMADY SLAVFGIGLK YLIPFMLLCL VCSALPALLQ AGFVLATEAL KPNLSALNPV 120
EGAKKLFSMR TVKDTVKTLL YLSSFVVAAI ICWKKYKVEI FSQLNGNIVG IAVIWRELLL 180
ALVLTCLACA LIVLLLDAIA EYFLTMKDMK MDKEEVKREM KEQEGNPEVK SKRREVHMEI 240
LSEQVKSDIE NSRLIVANPT HITIGIYFKP ELMPIPMISV YETNQRALAV RAYAEKVGVP 300
VIVDIKLARS LFKTHRRYDL VSLEEIDEVL RLLVWLEEVE NAGKDVIQPQ ENEVRH 356 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
 GO:0009306; P:protein secretion; IEA:InterPro. 
Interpro
 IPR006307; T3SS_EscU.
 IPR006135; T3SS_substrate_exporter. 
Pfam
 PF01312; Bac_export_2 
SMART
  
PROSITE
  
PRINTS
 PR00950; TYPE3IMSPROT.