UniProt Accession

 AT5G3_HUMAN; P48201; B2R4Z0; D3DPF0; Q4ZFX7 

Genbank Protein ID

 U09813; AK311999; AC096649; CH471058; CH471058; BC106881 

Genbank Nucleotide ID

 AAA78807.1; BAG34937.1; AAX88970.1; EAX11106.1; EAX11107.1; AAI06882.1 

Protein Name

 ATP synthase lipid-binding protein, mitochondrial 

Protein Synonyms/Alias

 ATP synthase proteolipid P3; ATPase protein 9; ATPase subunit c 

Gene Name

 ATP5G3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
6	**MFACAKLACTPSL	ubiquitination	[1, 2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. 

Sequence Annotation

  

Keyword

 CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Lipid-binding; Membrane; Mitochondrion; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 142 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; TAS:ProtInc.
 GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
 GO:0005215; F:transporter activity; NAS:ProtInc.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. 

Interpro

 IPR000454; ATPase_F0-cplx_csu.
 IPR020537; ATPase_F0-cplx_csu_DDCD_BS.
 IPR002379; ATPase_proteolipid_c_like_dom. 

Pfam

 PF00137; ATP-synt_C 

SMART

  

PROSITE

 PS00605; ATPASE_C 

PRINTS

 PR00124; ATPASEC.