UniProt Accession

 D6RG18_HUMAN; D6RG18 

Genbank Protein ID

 AC018754 

Genbank Nucleotide ID

  

Protein Name

 Cyclin-H 

Protein Synonyms/Alias

  

Gene Name

 CCNH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
115	ENPEILRKTADDFLN	ubiquitination	[1]
179	SQLLDIMKSMRNLVK	ubiquitination	[2]
232	DDDYVSKKSKHEEVC	ubiquitination	[2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Cyclin; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 255 AA 

Protein Sequence

Gene Ontology

 GO:0070985; C:TFIIK complex; IEA:InterPro.
 GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR013763; Cyclin-like.
 IPR015429; Cyclin_C/H/T/L.
 IPR006671; Cyclin_N.
 IPR023598; CyclinC.
 IPR027081; CyclinH/Ccl1. 

Pfam

 PF00134; Cyclin_N 

SMART

 SM00385; CYCLIN 

PROSITE

  

PRINTS