CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030570
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-tubulin complex component 2 
Protein Synonyms/Alias
 cDNA FLJ38768 fis, clone KIDNE2015313, highly similar to Gamma-tubulin complex component 2 
Gene Name
 TUBGCP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19IQEDYNDKYWDQRYTubiquitination[1, 2]
38QIPSFLQKMADKILSubiquitination[2]
48DKILSTGKYLNVVREubiquitination[2, 3, 4]
472LSAERSQKATPQVPVubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 495 AA 
Protein Sequence
MVEEHELRKE RIQEDYNDKY WDQRYTIVQQ QIPSFLQKMA DKILSTGKYL NVVRECGHDV 60
TCPVAKEIIY TLKERAYVEQ IEKAFNYASK VLLDFLMEEK ELVAHLRSIK RYFLMDQGDF 120
FVHFMDLAEE ELRKPVEDIT PPRLEALLEL ALRMSTANTD PFKDDLKIDL MPHDLITQLL 180
RVLAIETKQE KAMAHADPTE LALSGLEAFS FDYIVKWPLS LIINRKALTR YQMLFRHMFY 240
CKHVERQLCS VWISNKTAKQ HSLHSAQWFA GAFTLRQRML NFVQNIQYYM MFEVMEPTWH 300
ILEKNLKSAS NIDDVLGHHT GFLDTCLKDC MLTNPELLKV FSKLMSVCVM FTNCMQKFTQ 360
SMKLDGELGG QTLEHSTVLG LPAGAEERAR KELARKHLAE HADTVQLVSG FEATINKFDK 420
NFSAHLLDLL ARLSIYSTSD CEHGMASVIS RLDFNGFYTE RLERLSAERS QKATPQVPVL 480
RGPPAPAPRV AVTAQ 495 
Gene Ontology
 GO:0005813; C:centrosome; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0000922; C:spindle pole; IEA:InterPro.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR007259; Spc97_Spc98. 
Pfam
 PF04130; Spc97_Spc98 
SMART
  
PROSITE
  
PRINTS