CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042990
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Translation initiation factor eIF-2B subunit beta 
Protein Synonyms/Alias
  
Gene Name
 EIF2B2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19AVMSRVNKVIIGTKTubiquitination[1]
25NKVIIGTKTILANGAubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 86 AA 
Protein Sequence
ETTVMTDAAI FAVMSRVNKV IIGTKTILAN GALRAVTGTH TLALAAKHHS TPLIVCAPMF 60
KLSPQQVESR IIESVLLLLQ GLSFVT 86 
Gene Ontology
 GO:0044237; P:cellular metabolic process; IEA:InterPro. 
Interpro
 IPR000649; IF-2B-related. 
Pfam
 PF01008; IF-2B 
SMART
  
PROSITE
  
PRINTS