| Tag | Content |
|---|
| CPLM ID | CPLM-019403 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DnaJ homolog subfamily C member 1 |
Protein Synonyms/Alias | DnaJ protein homolog MTJ1 |
Gene Name | DNAJC1 |
Gene Synonyms/Alias | HTJ1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 260 | KETRLKEKEDALTRT | ubiquitination | [1] |
|
Reference | [1] Integrated proteomic analysis of post-translational modifications by serial enrichment. Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA. Nat Methods. 2013 Jul;10(7):634-7. [ PMID: 23749302] |
Functional Description | May modulate protein synthesis (By similarity). |
Sequence Annotation | DOMAIN 65 129 J.
DOMAIN 325 379 SANT 1.
DOMAIN 492 547 SANT 2.
MOD_RES 363 363 Phosphoserine (By similarity).
MOD_RES 365 365 Phosphothreonine (By similarity).
MOD_RES 381 381 Phosphoserine.
MOD_RES 430 430 Phosphoserine.
MOD_RES 479 479 Phosphoserine.
MOD_RES 480 480 Phosphoserine.
MOD_RES 484 484 Phosphoserine. |
Keyword | 3D-structure; Chaperone; Complete proteome; DNA-binding; Endoplasmic reticulum; Membrane; Microsome; Nucleus; Phosphoprotein; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 554 AA |
Protein Sequence | MTAPCSQPAQ LPGRRQLGLV PFPPPPPRTP LLWLLLLLLA AVAPARGWES GDLELFDLVE 60
EVQLNFYQFL GVQQDASSAD IRKAYRKLSL TLHPDKNKDE NAETQFRQLV AIYEVLKDDE 120
RRQRYDDILI NGLPDWRQPV FYYRRVRKMS NAELALLLFI ILTVGHYAVV WSIYLEKQLD 180
ELLSRKKREK KKKTGSKSVD VSKLGASEKN ERLLMKPQWH DLLPCKLGIW FCLTLKALPH 240
LIQDAGQFYA KYKETRLKEK EDALTRTELE TLQKQKKVKK PKPEFPVYTP LETTYIQSYD 300
HGTSIEEIEE QMDDWLENRN RTQKKQAPEW TEEDLSQLTR SMVKFPGGTP GRWEKIAHEL 360
GRSVTDVTTK AKQLKDSVTC SPGMVRLSEL KSTVQNSRPI KTATTLPDDM ITQREDAEGV 420
AAEEEQEGDS GEQETGATDA RPRRRKPARL LEATAKPEPE EKSRAKRQKD FDIAEQNESS 480
DEESLRKERA RSAEEPWTQN QQKLLELALQ QYPRGSSDRW DKIARCVPSK SKEDCIARYK 540
LLVELVQKKK QAKS 554 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. GO:0001671; F:ATPase activator activity; TAS:UniProtKB. GO:0003682; F:chromatin binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0045861; P:negative regulation of proteolysis; TAS:UniProtKB. GO:0006457; P:protein folding; IEA:Compara. GO:0050708; P:regulation of protein secretion; IDA:UniProtKB. GO:0006417; P:regulation of translation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |