CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027332
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fumarate hydratase, putative 
Protein Synonyms/Alias
  
Gene Name
 PFI1340w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
395CRYLDNLKTEGGIYGacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 681 AA 
Protein Sequence
MIKFKEASIL LSHKNAYLQY NLYFKKIRCV YHKIYRRHMN SLNSFIDILS FRNEDDIEYK 60
KVEDLSKYIE VIKINKSPMN ETKYYGYNFK EEYNFLDEHG NIKEYIYNEN KKLLYKNYEK 120
EYIHIPPFVL TKLCEYAFKE ILFFLNKKHL KQLQHILQDK ESSKNDKYVA MTLIKNAIIS 180
SEQKLPGCQD TGTAIILGKK DEDILTTYEH KYLTLGVYNA YKYNNFRYSQ LSPLNMFNEV 240
NTKNNLPCQI EIYTNIKKEK LHEVQQNEYP NHMKDIQNNN NVKHNKDITT RQIDSKENQK 300
STKKQNVDFL YDGPKYELIF IAKGGGSANK TFLFQQTKSI LNEENLYNFL LDKIKEIGTS 360
ACPPYHLAIV IGGLSAEMNL KMVKLASCRY LDNLKTEGGI YGKAFRDLES EKIILQKAQS 420
LGIGAQFGGK YFVHDVRVIR LPRHSASCPI GIGVSCSADR QIKCLINKNG VFMQMLEHEP 480
IKYLPEITFK DLNQENAVKI DLNQNMEQTL KTLSKYPTST LVLLTGKLVV ARDSAHKKIV 540
DQFINDNVPI PEYFKKYPIY YAGPAKTPDN YASGSFGPTT AGRMDAYAEV LMKNNASLIS 600
LAKGNRSAVV RNACKKYNGF YLGSIGGPGA ILAKNNIKNV QVIDFKDMGM EAVHLIDVVD 660
FPAFIVIDNK GNDFYNKWLP S 681 
Gene Ontology
 GO:0004333; F:fumarate hydratase activity; IEA:EC. 
Interpro
 IPR004646; Fe-S_hydro-lyase_TtdA-typ_cat.
 IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat. 
Pfam
 PF05681; Fumerase
 PF05683; Fumerase_C 
SMART
  
PROSITE
  
PRINTS