CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004401
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aromatic amino acid transport protein AroP 
Protein Synonyms/Alias
 General aromatic amino acid permease 
Gene Name
 aroP 
Gene Synonyms/Alias
 b0112; JW0108 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
329KALASVDKRGVPVNTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan). 
Sequence Annotation
  
Keyword
 Amino-acid transport; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 457 AA 
Protein Sequence
MMEGQQHGEQ LKRGLKNRHI QLIALGGAIG TGLFLGSASV IQSAGPGIIL GYAIAGFIAF 60
LIMRQLGEMV VEEPVAGSFS HFAYKYWGSF AGFASGWNYW VLYVLVAMAE LTAVGKYIQF 120
WYPEIPTWVS AAVFFVVINA INLTNVKVFG EMEFWFAIIK VIAVVAMIIF GGWLLFSGNG 180
GPQATVSNLW DQGGFLPHGF TGLVMMMAII MFSFGGLELV GITAAEADNP EQSIPKATNQ 240
VIYRILIFYI GSLAVLLSLM PWTRVTADTS PFVLIFHELG DTFVANALNI VVLTAALSVY 300
NSCVYCNSRM LFGLAQQGNA PKALASVDKR GVPVNTILVS ALVTALCVLI NYLAPESAFG 360
LLMALVVSAL VINWAMISLA HMKFRRAKQE QGVVTRFPAL LYPLGNWICL LFMAAVLVIM 420
LMTPGMAISV YLIPVWLIVL GIGYLFKEKT AKAVKAH 457 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:EcoCyc.
 GO:0015192; F:L-phenylalanine transmembrane transporter activity; IDA:EcoCyc.
 GO:0015196; F:L-tryptophan transmembrane transporter activity; IDA:EcoCyc.
 GO:0005302; F:L-tyrosine transmembrane transporter activity; IDA:EcoCyc.
 GO:0009977; F:proton motive force dependent protein transmembrane transporter activity; IDA:EcoCyc. 
Interpro
 IPR004841; AA-permease_dom.
 IPR002293; AA/rel_permease1.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
 PF00324; AA_permease 
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS