CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006973
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative aldehyde dehydrogenase-like protein YHR039C 
Protein Synonyms/Alias
 Meiotic sister-chromatid recombination protein 7 
Gene Name
 MSC7 
Gene Synonyms/Alias
 YHR039C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
143EMVSKAGKAQSTWGNubiquitination[1]
346YILKCAAKSLTPVVVubiquitination[1]
641KSLFSLAKEAS****ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 ACT_SITE 354 354 Proton acceptor (By similarity).
 ACT_SITE 389 389 Nucleophile (By similarity).
 CARBOHYD 15 15 N-linked (GlcNAc...) (Potential).
 CARBOHYD 565 565 N-linked (GlcNAc...) (Potential).
 CARBOHYD 627 627 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Endoplasmic reticulum; Glycoprotein; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 644 AA 
Protein Sequence
MSKVYLNSDM INHLNSTVQA YFNLWLEKQN AIMRSQPQII QDNQKLIGIT TLVASIFTLY 60
VLVKIISTPA KCSSSYKPVK FSLPAPEAAQ NNWKGKRSVS TNIWNPEEPN FIQCHCPATG 120
QYLGSFPSKT EADIDEMVSK AGKAQSTWGN SDFSRRLRVL ASLHDYILNN QDLIARVACR 180
DSGKTMLDAS MGEILVTLEK IQWTIKHGQR ALQPSRRPGP TNFFMKWYKG AEIRYEPLGV 240
ISSIVSWNYP FHNLLGPIIA ALFTGNAIVV KCSEQVVWSS EFFVELIRKC LEACDEDPDL 300
VQLCYCLPPT ENDDSANYFT SHPGFKHITF IGSQPVAHYI LKCAAKSLTP VVVELGGKDA 360
FIVLDSAKNL DALSSIIMRG TFQSSGQNCI GIERVIVSKE NYDDLVKILN DRMTANPLRQ 420
GSDIDHLENV DMGAMISDNR FDELEALVKD AVAKGARLLQ GGSRFKHPKY PQGHYFQPTL 480
LVDVTPEMKI AQNEVFGPIL VMMKAKNTDH CVQLANSAPF GLGGSVFGAD IKECNYVANS 540
LQTGNVAIND FATFYVCQLP FGGINGSGYG KFGGEEGLLG LCNAKSVCFD TLPFVSTQIP 600
KPLDYPIRNN AKAWNFVKSF IVGAYTNSTW QRIKSLFSLA KEAS 644 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
 GO:0007131; P:reciprocal meiotic recombination; IMP:SGD. 
Interpro
 IPR016161; Ald_DH/histidinol_DH.
 IPR016163; Ald_DH_C.
 IPR016160; Ald_DH_CS.
 IPR016162; Ald_DH_N.
 IPR015590; Aldehyde_DH_dom. 
Pfam
 PF00171; Aldedh 
SMART
  
PROSITE
 PS00070; ALDEHYDE_DEHYDR_CYS
 PS00687; ALDEHYDE_DEHYDR_GLU 
PRINTS